In the past two decades, increasing consumption of synthetic drugs and its associated side effects has led World Health Organization (WHO) to study the antioxidant activity of this plant. It also conducted an ethno botanical survey of endemic medicinal plants studying its uses by the rural populations in order to prevent and treat many current diseases (1). Achillea species such as Achillea mil...

BACKGROUND The dried root of Polygala tenuifolia, named Radix Polygalae, is a well-known traditional Chinese medicine. Triterpenoid saponins are some of the most important components of Radix Polygalae extracts and are widely studied because of their valuable pharmacological properties. However, the relationship between gene expression and triterpenoid saponin biosynthesis in P. tenuifolia is u...

According to distribution of genus Achillea, two main centers of diversity occur in S.E. Europe and S.W. Asia. Diversified essential oil compositions from Balkan Peninsula have been numerously reported. However, report on essential oils of Achillea species growing in Turkey, which is one of the main centers of diversity, is very limited. This paper represents the chemical compositions of the es...

Purpose: To gain insight into the mechanisms of analgesic and anti-inflammatory activities of the root extract of Polygala tenuifolia. Methods: Polygala tenuifolia was extracted with 70 % methanol and tested for analgesic and antiinflammatory activities (0.1, 1, 10 and 100 mg/kg) using the following models: acetic acid-induced writhing, rat paw edema, bradykinin inhibtion with rat ileum, and pr...

OBJECTIVE Achillea is a traditional medicinal herb which contains different phenol and flavonoid compounds that are responsible for Achillea pharmacological effects. We aimed to determine phenol and flavonoid contents, besides antioxidant activities of different extracts from Achillea eriophoraa (A. eriophora) DC. and Achillea biebersteinii (A. biebersteinii) Afan. (endemic species in Iran) and...

Interleukin-1β (IL-1β) has a role in β- cell destruction in autoimmune diabetes by stimulating the expression of inducible nitric oxide synthase (iNOS) that generates the free radical nitric oxide. We aimed to investigate the effect of Achillea millefolium L, as a traditional hypoglycemic agent, on IL-1β and iNOS gene expression of pancreatic tissue in the STZ- induced diabetic rats. Forty adul...

1. To study the potential for complementarity in nitrogen acquisition from different soil depths, we injected an isotope tracer ( 15 NH 4 Cl) at 5 and 20 cm depths in plant communities containing Achillea millefolium L. and Festuca ovina L. or Phleum pratense L. and Trifolium pratense L. in monocultures and two-species mixtures. 2. In monoculture, Festuca and Phleum took up tracer at 5 and 20 c...

BACKGROUND One of the best ways to control the malaria disease and to be protected human against Anopheles mosquito biting is the use of repellents. Throughout repellents, herbal ones may be an appropriate and safe source for protection. METHODS Chemical constituents of Achillea vermiculata and Satoreja hortensis were determined by using gas chromatography-mass spectrometry. Efficacy and the ...

Background and objectives: Achillea is an ancient medicinal herb. The genus comprises about 100 species which are mostly distributed in northern hemisphere and some have been investigated for different biological activities. There are also several reports in Iranian Traditional Medicine (ITM) texts about its anti-tumor effect. The cytotoxic activity of the methanol extract of Achillea vermicula...

Achillea millefolium L. (Asteraceae), popularly known as yarrow, has been used in traditional medicine to treat complaints such as gastrointestinal disturbances, hemorrhages, wounds, inflammation and pain. The aim of the present study was to assess the analgesic effects of aqueous extract of Achillea millefolium L. (AE) in the rat’s formalin test. Oral administration of different doses of AE (8...