Recent medical literature contains a number of case reports and series demonstrating the feasibility of this technology in many settings. These include mapping and ablation of tachycardias in the setting of complex congenital heart disease, more routine supraventricular tachycardias, and ventricular tachycardia. There has also been a small trial comparing transseptal versus retrograde aortic ap...

Two cases with a concealed left-sided accessory atrioventricular bypass tract are described. In both, functional longitudinal dissociation of the atrioventricular node narrowed the range of atrial premature beat coupling intervals which could initiate re-entry using the accessory pathway. In case 1 early premature atrial beats were followed by an atrioventricular nodal re-entrant echo. The atri...

OBJECTIVE To assess the efficacy and safety of intravenous dofetilide in preventing induction of atrioventricular re-entrant tachycardia. DESIGN A multicentre, open, dose ranging trial. Fifty one patients with electrically inducible atrioventricular re-entrant tachycardia were allocated to one of five doses of dofetilide (1.5, 3, 6, 9, and 15 microgram/kg), two thirds of the dofetilide dose b...

C ongenitally corrected transposition of the great arteries (ccTGA) is a rare cardiac malformation characterized by the combination of discordant atrioventricular and ventriculoarterial connections. The incidence has been reported to be around 1/33 000 live births, accounting for 0.05% of congenital heart malformations. Although a familial recurrence of heart defects in subjects with ccTGA has ...

Theoretical considerations indicate that complex patterns of atrioventricular conduction produced by rapid atrial stimulation can be predicted from changes in atrioventricular conduction produced by premature stimulation of the atrium. The purpose of this study was to evaluate the validity of this theoretical approach in seven patients undergoing electrophysiologic investigation. The atrioventr...

Sinus node recovery time was compared to the recovery time of a slow atrioventricular junctional rhythm in each of the same seven pentobarbital anesthetized dogs. Recovery time and the first five cardiac cycles were examined after pacing atria and ventricles for 20, 40, and 60 seconds at four or more pacing cycle lengths. Data relating recovery times and return to control conditions to prepacin...

BACKGROUND Cryoablation is increasingly utilized in children because of its safety profile. Recently, larger catheter tips have been more widely used to improve long-term success rates. The aim of this study was to assess the safety and efficacy of 8-mm-tip catheters for cryoablation of right-sided accessory pathways (APs) in children. METHODS Electrophysiological procedures were performed us...

A 19-year-old female underwent repair of complex congenital heart disease (atrial and ventricular septal defect with a supero-inferior ventricular relationship) in infancy. Because of recurrent palpitations she underwent an electrophysiology study. Atypical atrioventricular nodal reentrant tachycardia was diagnosed. Catheter ablation was performed successfully using cryothermal energy. The diag...

INTRODUCTION Left ventricular noncompaction (LVNC) is classified as a genetic cardiomyopathy characterized by a progressive systolic dysfunction. It may occur alone or in association with congenital cardiac anomalies. The combination of left ventricular noncompaction with partial atrioventricular canal defect is rare and has not, to our knowledge, been described previously. CASE PRESENTATION ...

Two patients who had an endocardial cushion type of ventricular septal defect underwent electrophysiologic studies for detection of specialized conduction tissue during operative repair. In one patient, with an inferior leftward frontal plane QRS axis on the ECG, we recorded an intraventricular His bundle electrogram anterior and superior to the ventricular septal defect. In the other patient, ...