The calculation of absorbed dose from internally incorporated radionuclides is based on the so-called specific absorbed fractions (SAFs) which represent the fraction of energy emitted in a given source region that is absorbed per unit mass in a specific target organ. Until recently, photon SAFs were calculated using MIRD-type mathematical phantoms. For electrons, the energy released was assumed...

We report the demonstration of a heat-fraction-limited CW Yb:YAG laser operating near 77 K with output at 1029 nm, pumped with a diffraction-limited room-temperature CW Nd:YAG laser operating at 946 nm. With a 50% reflectivity outcoupler, the average threshold absorbed pump power was 18.8 mW and the average slope efficiency 91.9%, close to the heat-fraction limited value of 91.5%. Average optic...

To understand luminous AGNs in the z < 1 universe, the ASCA AGN samples are the best at present. Combining the identified sample of AGNs from ASCA Large Sky Survey and Medium Sensitivity Survey, the sample of hard X-ray selected AGNs have been expanded up to 108 AGNs above the flux limit of 10 erg s cm in the 2–10 keV hard X-ray band. We discuss the fraction of absorbed AGNs in the hard X-ray s...

328 words Introduction: 420 words Discussion: 1403 words Abbreviations: AUC, area under the curve; CL, clearance, Cmax, maximum concentration; F, bioavailability; Fa, fraction absorbed; Fg, fraction escaping gut wall elimination; Fh, fraction escaping hepatic elimination; HLM, human liver microsomes; PK, pharmacokinetics, SD, standard deviation; tmax, time to reach Cmax. This article has not be...

Introduction: Cancer is, in essence, a genetic disease and is the second leading cause of death globally. Fortunately, many common types of cancer are treatable if detected early and of course there are many medications and treatments available today. Among the new methods to treat cancer, radiotherapy seems to be hopeful in patients with malignancies. This work investigates th...

To determine the opsonic effect of antibodies to Actinobacillus (Haemophilus) pleuropneumoniae outer membrane proteins on phagocytosis by porcine polymorphonuclear leukocytes (PMN), we separated the integral outer membrane proteins (IOMPs) by Triton X-114 extraction. Four major IOMPs with molecular masses of 76, 50, 39, and 29 kDa were detected by sodium dodecyl sulfate-polyacrylamide gel elect...

Introduction: Nuclear medicine techniques have been widely employed in the assessment of gastroesophageal dysfunction. Gastroesophageal reflux (GER) is a common, self-limited process in infants and children that usually resolves at 12 to 18 months of age. Clinical management of GER includes conservative treatment, thickened feedings, positional therapy and parental reassurance. On the other han...

Background: Most preclinical studies are carried out on mice. For internal dose assessment of a mouse, specific absorbed fraction (SAF) values play an important role. In most studies, SAF values are estimated using older standard human organ compositions and values for limited source target pairs.Objective: SAF values for monoenergetic photons of energies 15, 50, 100, 500, 1000 and 4000 keV...