background: glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most common enzyme disorder in human. the aim of this study was to determine the prevalence of g6pd deficiency among children and evaluate its association with abo/rh blood groups.   method: blood samples of 3401 asymptomatic children were analyzed and compared with 317 children who were admitted to hospital because of hemol...

We experienced a case with suspected drug-induced Hemolytic Uremic Syndrome (HUS) by immunosuppressive drug cyclosporine (CYA). HUS developed in a 51-yearold woman treated with CYA after ABO blood type Incompatible Living Donor Renal Transplant (ILDRTx). Her blood type was A positive, underwent ILDRTx from her husband whose blood type was B positive. She had developed hemolytic anemia with eryt...

background & aims: mistyping either a donor or a recipient can lead to transfusion with abo incompatible blood which results in severe intravascular hemolysis and may even result in the death of the recipient. abo phenotype is one of the essential tests in immunohematology. eighty percent of blood group a and ab persons are subtype a1 and a1b, respectively. the other 20% of these blood groups a...

ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowle...

The paper discusses effects of natural selection on four population groups of Orissa in the form of differential fertility and mortality as a consequence of ABO incompaptibity. The negative effect of ABO incompatibility is not fully manifested in terms of significant decrease in the viability of foetus and children. However, incidences of abortion, stillbirth and post-natal mortality are margin...

There are three common alleles (A, B, and O) at the human ABO blood group locus. We compared nucleotide sequences of these alleles, and relatively large numbers of nucleotide differences were found among them. These differences correspond to the divergence time of at least a few million years, which is unusually large for a human allelic divergence under neutral evolution. We constructed phylog...

INTRODUCTION In order to diagnose hemolytic disease of the newborn it is necessary to determine ABO/Rh blood group, direct antiglobulin test and indirect antiglobulin test in newborns as well as ABO/Rh and indirect antiglobulin test in their mothers due to a possible incompatibility between the blood types of the mother and her baby. The study was aimed at reviewing and analyzing the results of...

Since the first link between blood type and cancer was described in 1953, numerous studies have sought to determine whether the histoblood ABO group is associated with tumorigenesis. In 2009, the first significant association between a SNP located within the ABO glycosyltransferase gene and increased risk of pancreatic cancer was reported. Here, we describe the history and possible functions of...

Many studies of ABO isolysins have indicated that some A, B, and O sera show no isohemolytic activity. The apparent incidence of ABO isolysins in human sera varies widely, from 0.24 of A sera containing anti-B isolysin [8] to more than 90 "6 of 0 and B sera containing anti-A isolysin [4]. Reports of many other wide-ranging values have led t o the general assumption that isolysins, in contrast t...

ABO antibodies (isoagglutinins) represent a formidable barrier to optimizing live donation and organ distribution. Blood group antigens are expressed on the endothelium of solid organs, and transplantation across a blood group barrier can result in hyperacute or acute antibody-mediated rejection (AMR). Based on blood group distributions in the United States, there is a 36% probability that any ...