Many diseases and genetic disorders are associated with ABO and Rh systems of blood antigens. This study was conducted to determine the frequency of ABO and Rhesus (Rh) blood groups in District Rahim Yar Khan, Pakistan so that the results could be used for further application. A total of 9891 subjects including patients and healthy individual were sampled only belonging to District Rahim Yar Kh...

Background: Vitiligo is a common disease. Its etiology is not known, but 30% of patients have a positive family history. Studies have been done on the influence of ABO and Rh blood groups on susceptibility to some diseases. Objective: The purpose of this case-control study was to evaluate the association of ABO and Rh blood groups with vitiligo. Patients and Methods: This study was performed on...

To assess the observation that blood type B might be a marker for longevity, we reviewed the records and determined the ABO blood types of all patients who died in our hospital in 2004. Age was stratified by decade of death, and linear regressions were calculated by ABO percentage. ABO survival curves were compared. In 2004, 906 patients died; 35 were excluded (stillborn infants). Of the remain...

ABO blood groups have long been associated with cardiovascular disease, thrombosis, and acute coronary syndromes. Many studies over the years have shown type O blood group to be associated with lower risk of cardiovascular disease than non-type O blood groups. However, the mechanisms underlying this association remain unclear. Although ABO blood group is associated with variations in concentrat...

Detection of ABO blood groups through agglutination is the basis of pre-transfusion testing. However, weak agglutination reactions may be obtained with reagent antibodies and are a result of weak expression of A and B antigens on red blood cell surface which may cause a discrepancy in blood group typing. Here, we report a donor which showed discrepancy between red blood cells (forward) and seru...

Introduction. Peripheral artery disease (PAD) is a common complication of diabetes mellitus (DM), affecting up to 20% people over 65. Blood type hypothesized influence PAD, although it has yet be extensively studied. We aim investigate the correlation between ABO blood group and severity PAD in patients with II DM.

Recent studies have reported that the ABO gene can affect circulating expression levels of soluble intercellular adhesion molecule 1 (sICAM-1) and soluble P-selectin (sP-selectin) in Caucasians. However, several factors may affect the association, including the distribution and variations of the ABO gene, ethnic diversity and the inflammatory response status. The aim of the present study was to...

INTRODUCTION The study was conducted to determine for the first time the association between the erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in malaria patients living in Thies, a hypoendemic area in Senegal. METHODOLOGY In 2007, the EBA-175 alleles and blood group types were determined by nested PCR and the Simonin test respectively in blood samples obtained from u...

ABO blood group antigens are complex carbohydrate molecules expressed on red blood cells and a variety of tissues. The ABO blood type is implicated in the development of a number of human diseases and there is increasing evidence regarding its involvement in the pathogenesis of cardiovascular disorders, mainly through its effect on von Willebrand factor levels. In this review, after a brief ana...

BACKGROUND: The ABO blood groups result from DNA sequence variations, predominantly single nucleotide and insertion/deletion polymorphisms (SNPs and indels), in the ABO gene encoding a glycosyltransferase. The ABO blood groups A(1), A(2), B and O predominantly result from the wild type allele A1 and the major gene variants that are characterized by four diallelic markers (261G>del, 802G>A, 803G...