Background: Radiotherapy is regarded as a standard treatment modality in breast cancer (BC). Radiation causes cellular damage both in cancer and normal cells by inducing DNA-damage and chromosomal aberrations (CA). Different agents were used for ameliorating effects of radiation, mainly antioxidants such as melatonin. Melatonin shows oncostatic properties on human BC. The aim of this study was ...

purpose: to investigate the relationship between higher-order aberrations (hoas) and contrast sensitivity function (csf) in myopes. methods: in this cross-sectional study, hoas and csf were measured in myopic eyes over a 6-mm pupil. pupil diameter was measured in photopic condition. the correlation between hoas and csf was investigated using multivariate linear regression analysis. results: sev...

conclusions it was demonstrated that the presence of del6q21 in b-cll patients indicates poor prognosis and on the contrary, presence of del17p13 points at the good prognostic value of the disease. results deletion of 17p13 was found in 11 (16.6%) and deletion 6q21 was present in 5 (7.5%). statistical analyses were performed to investigate the correlation of these molecular-cytogenetic findings...

background: induction of radioadaptive responses in cells pretreated with a low dose radiation before exposure to a high dose is well documented by many investigators. the aim of this study is to determine the frequency of chromosomal aberration in peripheral blood lymphocytes of patients treated by radioiodine (131i) for hyperthyroidism, with or without previous thyroid scan with 99mtc. materi...

Active optics and aberration correction techniques for sparse aperture segmented mirrors are studied. A finite element model of the mirror was established, a multi-aperture polynomial derived. According to hard spot theorem, co-phase maintenance method based on change edge sensor position in conventional mode is And surface without participation proposed. The can correct aberrations surface, wh...

PURPOSE To compare total ocular aberrations and corneal aberrations identified with four different aberrometers and to determine the repeatability and interobserver variability. METHODS In this prospective comparative study, 23 healthy subjects underwent bilateral examination with four aberrometers: the Irx3 (Hartmann-Shack; Imagine Eyes, Orsay, France), Keratron (Hartmann-Shack; Optikon, Rom...

The GRAVITY instrument on the ESO VLTI pioneers field of high-precision near-infrared interferometry by providing astrometry at $10 - 100\,\mu$as level. Measurements such high precision crucially depend control systematic effects. Here, we investigate how aberrations introduced small optical imperfections along path from telescope to detector affect astrometry. We develop an analytical model th...

The use of a multichannel wavefront sensor matched with phase Zernike functions to determine the type and magnitude aberration in analyzed is investigated. approach based on stepwise compensation aberrations dynamically tunable spatial light modulator. As criteria for successful detection, not only correlation peak, but also maximum intensity, compactness, orientation distribution each diffract...

Clonal cytogenetic aberrations of the Philadelphia chromosome (Ph) positive hematopoiesis have been associated with the natural evolution of chronic myeloid leukemia (CML) to advanced disease. Clonal aberrations of Ph negative metaphases have been described after treatment with interferon or imatinib. This study evaluates the effect of dasatinib on Ph positive clones with additional cytogenetic...