Background & aims: Adhesion and fibrotic bands formation is one of the most important post-surgical complication in pelvic and abdominal surgeries. Major studies in prevention of adhesion formation have based on antioxidant and anti-inflammatory agents. Silymarin, Silybum marianum extract contains compounds with antioxidant, anti-inflammatory and fibrinolytic activities thus could reduce adhesi...

Objective: The aim of this study was to compare the use of Polypropylene mesh (Prolene) and Sepramesh, a coated Polypropylene mesh with a protective layer of Seprafilm on its visceral side, for the repair of abdominal wall defects in horses. We also aimed to quantify the consequent visceral adhesion and tissue inflammatio Design: Experimental study. Animals: Ten horses. Methods: The horses w...

background: adhesion is a common complication of gynecology surgery so different barrier agents and solutions have been used during these operations to separate and protect tissues from adhesion after surgery. adept is one of these solutions that have been postulated to reduce the chance of adhesion following gynecolgy surgery. objective: to evaluate the effect of 4% icodextrin in reducing adhe...

Abdominal adhesions, whether caused by peritoneal trauma, radiation, infection, or a congenital condition, are associated with a wide range of complications. These complications include chronic abdominal or pelvic pain, infertility, and adhesive small bowel obstruction. Such adhesions render re-operation difficult, with attendant risks of inadvertent enterostomy and increased operation time. Th...

We observed the inhibitive effect of electroacupuncture (EA) at Zusanli on inflammatory mediators of postoperative intra-abdominal adhesions to find out the relationship between EA and the cholinergic anti-inflammatory pathway. Sixty-four rats were divided into 8 groups (A-H, each = 8): A = sham control; B = abdominal adhesions model; C = abdominal adhesions plus EA; D = sham acupoint control; ...

Study Objective. Evaluation of SprayShieldTM Adhesion Barrier System efficacy in the rat cecum and porcine abdominal sidewall adhesion model. Design. Rat Model: Evaluation of SprayShieldTM adhesion prevention relative to Control animals. Porcine Model: Evaluation of SprayShieldTM Adhesion Barrier System and SprayGelTM Adhesion Barrier vs. Control in a porcine abdominal sidewall injury model. Se...

BACKGROUND Therapeutic hypothermia during operation decreases postoperative intra-abdominal adhesion formation. We sought to determine the most appropriate duration of hypothermia, and whether hypothermia affects the expression of tissue plasminogen activator (tPA). METHODS 80 male BALB/c mice weighing 25-30 g are randomized into one of five groups: adhesion model with infusion of 15°C saline...

BACKGROUND Abdominal operations are followed by adhesions, a prevalent cause of abdominal pain, and the most frequent cause for bowel obstruction and secondary female infertility. This rat study addresses adhesion prevention capability of Adept(®), Interceed(®), Seprafilm(®), and a novel device, 4DryField(®) PH which is provided as powder and generates its effect as gel. METHODS Sixty-eight m...