The PFDB (Protein Family Database) is a new database designed to integrate protein family-related data with relevant functional and genomic data. It currently manages biological data for three projects – the CATH protein domain database (Orengo et al., 1997; Pearl et al., 2001), the VIDA virus domains database (Albà et al., 2001) and the Gene3D database (Buchan et al. 2001). The PFDB has been d...

INTRODUCTION Individual patient data (IPD) meta-analysis (MA) offers advantages over aggregate MA of using standardised criteria for patient characteristics across trials, and allowing reliable investigation of subgroup effects of interventions. Network meta-analysis (NMA) allows for the comparison of multiple treatments in a comprehensive analysis and the determination of the best treatment am...

The database model presented in this paper is suitable for application in which queries may require non-crisp references to certain attributes. The data item (attribute) values may be crisp or fuzzy. For instance, such adjectives as 'high' or 'normal' may be attribute values for the attribute blood pressure. A disease or a condition can be described by a number of symptoms which may be crisp al...

ion: Meta-data are given at different levels of abstraction, a conceptual (abstract) and a relational (executable) level. The same case at the conceptual level can be mapped on several different cases at the relational level. This makes an abstract case re-usable. Ease of case adaptation: In order to run a given sequence of operators on a new database, only the relational meta-data and their ma...

BACKGROUND It has long been intriguing scientists to effectively compare different microbial communities (also referred as 'metagenomic samples' here) in a large scale: given a set of unknown samples, find similar metagenomic samples from a large repository and examine how similar these samples are. With the current metagenomic samples accumulated, it is possible to build a database of metageno...

MOTIVATION The PFDB (Protein Family Database) is a new database designed to integrate protein family-related data with relevant functional and genomic data. It currently manages biological data for three projects-the CATH protein domain database (Orengo et al., 1997; Pearl et al., 2001), the VIDA virus domains database (Albà et al., 2001) and the Gene3D database (Buchan et al., 2001). The PFDB ...

introduction : the aim of this quantitative systematic review/meta-analysis was to compare the treatment outcomes of mineral trioxide aggregate (mta) and calcium hydroxide (ch) in pulpotomy of human primary molars. the focused pico question was “in case of pulp exposure in vital primary molars, how does mta pulpotomy compare to ch in terms of clinical/radiographic success?” methods and material...

A data warehouse is simply a single, complete, and consistent store of data obtain from a variety of sources and made available to end users in a way they can understand and use in a business context. To manage and maintain the heterogeneous data source and huge amount data of a data warehouse, much research has been done in the topic called Meta-Data management system. Current research for Met...

BACKGROUND A large number of randomized controlled studies have clearly demonstrated that psychological interventions are effective in the treatment of depression. The number of studies in this area is increasing rapidly. In this paper, we present a database of controlled and comparative outcome studies on psychological treatments of depression, based on a series of meta-analyses published by o...

Deductive databases manage large quantities of data and, in general, in a set-oriented way. The existing systems of explanation for deductive databases do not take these constraints into account. We propose a tracing technique which consists of integrating a "relational" trace and an instrumented meta-interpreter using substitution sets. The relational trace e ciently gives precise information ...