Methods of increasing the performance of radionuclide generators used in nuclear medicine radiotherapy and SPECT/PET imaging were developed and detailed for 99Mo/99mTc and 68Ge/68Ga radionuclide generators as the cases. Optimisation methods of the daughter nuclide build-up versus stand-by time and/or specific activity using mean progress functions were developed for increasing the performance o...

I am so honored to serve as SNMMI’s 2016–2017 president. Seeing all the exciting research presented at the society’s Annual Meeting in San Diego, CA, has certainly energized me for the year ahead. I am indeed fortunate to be following Dr. Hossein Jadvar as president. Thanks to his leadership, the Therapy Center of Excellence (CoE) was established to support the development and utilization of ta...

Objective: The new Ultra-TechneKowt Dry Ship Top Elute 99mTc generator (UTKt-DTE generator; Mallinckrodt Medical, Inc., St. Louis, MO) was devised to facilitate fractionated elution with an ergonomically designed elution shield. Fractionation is accomplished traditionally by visually observing the eluted volume through 2 layers of leaded glass windows located in a lighted elution shield and gen...

OBJECTIVE Chemical reactions involved in preparing 99mTc radiopharmaceuticals occasionally result in products of substandard purity. A retrospective examination of preparation problems that occurred in the author's institution was conducted to better define the incidence, recognize patterns and identify causes of substandard 99mTc radiopharmaceutical products. METHODS All 99mTc radiopharmaceu...