Background: Few previous studies have investigated the incidence rate (IR) and point prevalence (PP) of seropositive seronegative rheumatoid arthritis (RA), further, estimates remain unknown in Danish population. Objectives: To investigate IR PP RA adult population from 1998 to 2018 using four register-based case definitions RA. Methods: Nationwide cohort study. Using administrative registers, ...

Book Reviews Carl M. Mansfield (ed.) Therapeutic Radiology; 2nd ed. Elsevier, Amsterdam 1988 XI+ 596 pp. US$ 85.-/DA. 215.ISBN 0-444-01317-2 The second edition of the well-known monograph edited by Carl M. Mansfield is a thorough review of therapeutic radiology. In the first 6 chapters, basic principles of radiobiology, radiologic investigations and radiation therapy treatment planning are ente...

Cholangiocarcinoma is a highly malignant neoplasm of the biliary tree. It has a high rate of mortality, and currently, there is no effective chemoprevention and treatment. This study was designed to investigate the potential effect of W3 polyunsaturated fatty acids (W3-PUFA) on human cholangiocarcinoma cell growth and to determine their mechanisms of actions. Treatment of three human cholangioc...

sing Na/Ca exchanger function during the cardiac cycle Dear Sir, are intriguing but depend greatly on the assumption that We have read with great interest Dr Isenberg’s editorial cytoplasmic [Na] is 9.6 mM. We will comment on this [1] published with our article [2] in Cardiovascular later. There are two further points to make regarding the Research. Dr Isenberg’s analysis highlights the numerou...

We adapted a commercially available flow-injection autoanalyzer (Lachat Quik-Chem 8000) to measure seawater nitrate concentrations at a rate of nearly 0.1 Hz and phosphate and silicate concentrations at a rate half that. Several minor improvements, including reduced sample-loop size, high sample flushing rate, modified carrier chemistry, and use of peak height rather than peak area as a proxy f...

•Characterization methods for CO2R catalysts that neglect mass transfer are inaccurate•CMA-ES coupled with continuum modeling rigorously parameterizes literature data•Fit parameters broadly distributed, suggesting differences in catalyst structure•Presented method is applicable to any electrochemical system affected by Electrochemical synthesis processes (e.g., the reduction of carbon dioxide [...

•A transient microscopic method for measuring thermal conductivity in single cells•Distinct living and dead cells normal cancer cells•First report of cell-level regulation according to ambient temperature•Cell metabolomic analysis unfold the mechanism cellular As basic unit life, carry out complex life activities all time. This activity is accompanied by continuous heat generation, transmission...