نتایج جستجو برای: 7 hydroxycoumarinyl gallates derivative

تعداد نتایج: 701784  

Journal: :journal of reports in pharmaceutical sciences 0
hadi  adibi department of medicinal chemistry, faculty of pharmacy, kermanshah university of medical sciences, kermanshah 67145-1673, iran leila hosseinzadeh sepideh farhadi farahnaz ahmadi

a green and efficient one-pot, four-component synthesis of 6-amino-4-aryl-3-methyl-2,4-dihydropyrano[2,3- c ]pyrazo-carbonitrile derivatives catalyzed by borax in water is described. this method provides several advantages such as environmental friendliness, shorter reaction time, excellent yields, and simple workup procedure. the in vitro cytotoxic activity of the synthesized test compounds wa...

Journal: :Bioscience, biotechnology, and biochemistry 2004
Fumiko Hayakawa Yoko Ishizu Nobuo Hoshino Akira Yamaji Takashi Ando Takahide Kimura

The ability of various tea catechins to generate H2O2 and the hydroxyl radical in the presence of the Cu2+ ion was investigated and compared with the effect of iron ions. The presence of Cu2+ accelerated the generation of H2O2 by EGC, while EGCg with Cu2+ generated a little H2O2. The presence of iron ions inhibited the generation of H2O2 by EGC. EGC and EC with Cu2+ generated the hydroxyl radic...

Journal: :Chemistry of Natural Compounds 2021

Two series of podophyllotoxin derivatives were synthesized by addition a 4?-sulfanilamide to or substitution 4?-amide into podophyllotoxin. Their cytotoxicities evaluated against four human cancer cell lines (A549, HeLa, MCF-7, and PC-3). Investigations the structure–activity relationship generalized. Derivative 9f (2-thienoylaminoepipodophyllotoxin) exhibited highest activity cells, inhibiting...

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