Abstract Coumarin and its nitrogen analogue 1-aza coumarin are a class of lactones lactams, respectively, which indispensable heterocyclic units to both chemists biochemists. 1-Aza derivatives, ultimately metabolize as the corresponding 8-hydroxy coumarins in biological system therefore found be very good anti-inflammatory, anti-cancer, analgesic agents. A series hybrid substituted azacoumarin-...

The coupling of coumarins with alkynes is described, which proceeds through a palladium-catalyzed cascade sequence. This process provides a new route to the synthesis of highly substituted cyclopentadiene fused chromones.

Five isoflavonoids, i.e. 5-hydroxy-7-methoxy-2’, 5’-dihydroxyisoflavone (AV4), 5, 7-dihydroxy-4’-methoxyisoflavone (AV6), 7-methoxy-5-hydroxy-4’-methoxy-2’-hydroxyisoflavone (AV7), 8-pregnyl genistein (AV9), 5,7-dihydroxy-8-pregnyl-4’-methoxy-2’-hydroxyisoflavone (AV10) and one coumarochromone – sophorophenolone (AV8) were isolated from EtOAc of in vitro callus cultures Astragalus vesicarius ss...

Nocardia cultures, isolated from soil by use of n-paraffins as the sole carbon source, have been shown to bring about significant oxidation of several methyl-substituted mono- and dicyclic aromatic hydrocarbons. Oxygen uptake by washed cell suspensions was not a reliable indicator of oxidation. Under co-oxidation conditions in shaken flasks, o- and p-xylenes were oxidized to their respective mo...

Phenolic compounds present in Lolium multiflorum Lam. were isolated and characterized. Significant differences in their distribution were found, in shoots and roots of plants with (Lmþ) and without (Lm ) endophyte association, grown with (Micþ) and without (Mic ) mycorrhizal fungi Glomus intraradices, indicating a systemic effect of these microorganisms on the phenolics metabolism of L. multifl...

6-Formyl-7-hydroxy-5-methoxy-2-methylchromone on bromination yields the 8-bromo deriva­ tive or the 8-bromo-6-formyl-5,7-dihydroxy derivative depending on the reaction condition. Cyclization of both leads to the corresponding 3-acetyl-, 3-benzoyl-, 3-carboxamido-, 3-carbethoxybenzodipyran derivatives. The 3-acetylbenzodipyran derivative when treated with ethyl acetoacetate or ethyl cyanoacetate...

In the present work the effect of different concentration of halide quenchers (Cl, Br, I) on 4-methyl-5-ethoxy-7-methoxy coumarin (1) and 4-methyl-5,7-diethoxy coumarin (2) in aqueous solutions have been carried out at 20 temperature. It was observed that the fluorescence intensity of these coumarin derivatives decrease with increase in the concentration of the quenchers except Cl quencher. Fur...