A Bounded Disorder file [9] [11] is a mechanism for maintaining files in traditional. systems. It guarantees good performance for single-key operations (e.g. search, insert, and delete), similar to that of hash based methods, and in addition, good performance for subrange operations, and reasonable performance for sequential-key operations (Le. subrange operations for which the output must be p...

At present, meprobamate is not a drug with a broad commercial spectrum. In order to get an optimal pharmaceutical formulation for this kind of drug or others more competitive, experimental design methodology is a statistical tool very useful for reach them. The principal aim of this work was to apply D-Optimal mixture design for optimization of meprobamate (400 mg) fast released tablets manufac...