The behavior of the compound [RuCl(cym)(H2biim)][BAr'4] (cym = eta6-para-isopropylmethylbenzene, Ar' = 3,5-bis(trifluoromethyl)phenyl), synthesized from [[RuCl(cym)]2(mu-Cl)2], H2biim and NaBAr'4, has been studied as a receptor of anions both in solution and in the solid state.

Treatment of AZ-521 cells with Helicobacter pylori VacA increased cyclooxygenase 2 (COX-2) mRNA in a time- and dose-dependent manner. A p38 mitogen-activated protein kinase (MAPK) inhibitor, SB203580, blocked elevation of COX-2 mRNA levels, whereas PD98059, which blocks the Erk1/2 cascade, partially suppressed the increase. Consistent with involvement of p38 MAPK, VacA-induced accumulation of C...

Retinal extracts of Gekko gekko were found to contain two retinene(1) photopigments, one with maximum absorption at about 521 mmicro, the second with a maximum in the region of 478 mmicro. These pigments were assayed by the method of partial bleaching and their spectral characteristics studied by examining their difference spectra. The 478 mmicro pigment was present in the extracts as 8 per cen...

Innovative applications of cell therapy products (CTPs) derived from human pluripotent stem cells (hPSCs) in regenerative medicine are currently being developed. The presence of residual undifferentiated hPSCs in CTPs is a quality concern associated with tumorigencity. However, no simple in vitro method for direct detection of undifferentiated hPSCs that contaminate CTPs has been developed. Her...

Kainate receptors (KARs), a family of ionotropic glutamate receptors, are widely expressed in the central nervous system and are critically involved in synaptic transmission. KAR activation is influenced by metabotropic glutamate receptor (mGlu) signaling, but the underlying mechanisms are not understood. We undertook studies to examine how mGlu modulation affects activation of KARs. Confocal i...

REASONING ON MISTAKES FOR FEEDBACK GENERATION Rodolfo Delmonte°, Dario Bianchi* °Department of Language Sciences Università Ca' Foscari Ca' GarzoniMoro San Marco, 3417 30124 Venezia (Italy) Tel.:041-2578464/52/19 E-mail:[email protected] WebSite:byron.cgm.unive.it *Dipartimento di Ingegneria dell'Informazione phone +39 521 905734 Universita' degli Studi di Parma fax +39 521 905723 43100 Parma It...

Many of the basic concepts of green chemistry are familiar to pollution prevention practitioners. The concepts of substituting less hazardous materials into chemical formulations and reducing wastes have been around for many years. Green chemistry has taken these concepts and expanded the scope of possibilities by fully evaluating all aspects of chemical reactions, processes and formulations. T...

Chronic kidney disease (CKD) affects the nonrenal clearance of drugs by modulating the functional expression of hepatic drug– metabolizing enzymes and transporters. The impact of CKD on oxidative and conjugative metabolism has been extensively studied. However, its effect on hepatic drug reduction, an important phase I drug–metabolism pathway, has not been investigated. We aimed to assess the e...

Hydroxylamine oxidoreductase (HAO) catalyzes the oxidation of hydroxylamine to nitrite in Nitrosomonas europaea. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is believed to be cytochrome c-554 (Cyt c-554). We have isolated a genomic DNA fragment containing the structural gene encoding ...