High-field arterial spin labeling (ASL) perfusion MRI is appealing because it provides not only increased signal-to-noise ratio (SNR), but also advantages in terms of labeling due to the increased relaxation time T(1) of labeled blood. In the present study, we provide a theoretical framework for the dependence of the ASL signal on the static field strength, followed by experimental validation i...

HER2, an oncogenic receptor is overexpressed in about 25-30% of breast cancer patients. HER2 has been shown to play role in tumor promotion by having cross-talk with multiple oncogenic pathways in cancer cells. Our results show that Cucurbitacin B (CuB), a triterpenoid steroidal compound inhibited the growth of various breast cancer cells with an IC50 ranging from 18-50nM after 48 and 72 h of t...

This study examined the possibility that pudendal nerve stimulation (PNS) or tibial nerve stimulation (TNS) inhibits the excitatory pathway from the pontine micturition center (PMC) to the urinary bladder. In decerebrate cats under α-chloralose anesthesia, electrical stimulation of the PMC (40 Hz frequency, 0.2-ms pulse width, 10-25 s duration) using a microelectrode induced bladder contraction...

Bacillus solimangrovi GH 2-4T was isolated from mangrove soil and subjected to whole genome sequencing on HiSeq platform and annotated on RAST. The nucleotide sequence of this genome was deposited into DDBJ/EMBL/GenBank under the accession MJEH00000000.

Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-mediated transcription factor playing key roles in glucose and lipid homeostasis, and PPARγ ligands possess therapeutic potential in these as well as other areas. In this study, a series of phenylthiazole acids have been synthesized and evaluated for agonistic activity by a convenient fluorescence polarization-based PPARγ liga...

The ground-state properties of the t-J model on a d-dimensional hypercubic lattice are examined in the limit of large d . It is found that the undoped system is an ordered antiferromagnet, and that the doped system phase separates into a hole-free antiferromagnetic phase and a hole-rich phase. The latter is electron free if J.4t and is weakly metallic ~and typically superconducting! if J,4t . T...

The four-triangles longest-edge (4T-LE) partition of a triangle t is obtained by joining the midpoint of the longest edge of t to the opposite vertex and to the midpoints of the two remaining edges. The so-called self-improvement property of the refinement algorithm based on the 4-triangles longest-edge partition is discussed and delimited by studying the number of dissimilar triangles arising ...

Secure function computation has been thoroughly studied and optimized in the past decades. We extend techniques used for secure to simulate arbitrary protocols involving a mediator. The key feature of our notion simulation is that it bidirectional: not only does produce outputs could happen original protocol, but produces all such outputs. In synchronous system, can be shown this requirement al...

In this paper average power consumption of dram cell designs have been analyzed for the nanometer scale memories. Many modern processors use dram for on chip data and program memory. The major contributor of power in dram is the off state leakage current. Improving the power efficiency of a dram cell is critical for the improvement in average power consumption of the overall system. 3T dram cel...