نتایج جستجو برای: 499 colon cancer
تعداد نتایج: 951274 فیلتر نتایج به سال:
background the sitting position, rather than squatting, during defecation has been hypothesized to be a risk factor for colorectal cancer (crc). methods we conducted a case-control study to test this hypothesis. a total of 100 crc cases from two hospitals in iran and 100 control subjects, selected from the coronary care unit (ccu) of those same hospitals were selected for this study. we adminis...
curcumin exhibits both cancer- preventive activity and growth inhibitory effects on several neoplastic cells including human colon cancer. serotonin and its receptors have also been implicated in tumor development. this study investigated the effect of ritanserin, a selective serotonin 5ht2a receptor antagonist, alone and in combination with curcumin on colorectal cancer cell lines. results sho...
background: colon cancer is the third cause of cancer deaths. although colon cancer survival time has increased in recent years, the mortality rate is still high. the cox model is the most common regression model often used in medical research in survival analysis, but most of the time the effect of at least one of the independent factors changes over time, so the model cannot be used. in the c...
Objective(s): The preclinical reports have shown that specific probiotics like Bifidobacterium bifidum (B. bifidum) and Lactobacillus acidophilus (L. acidophilus) can be applied as the biotherapeutic agents in the inhibition or therapy of colorectal cancer via the modification of gut bacteria. In the previous studies, we have assessed the impact of L. acidophilus and B...
Introduction: Colon cancer is the fourth cause of mortality at the world and second common cancer in the Europe. About 8% of all cancer deaths are due to colon cancer. This condition is caused by abnormal growth of cells which can invade or multiply in other tissues of the body (metastasis). The present study was designed to investigate the Simultaneous effect of quercetin and exercises on oxid...
Objective(s): Several beneficial effects have been attributed to the probiotic lactic acid bacteria. It was determined that lactobacilli can exert antiproliferative effects on the various cancer cell lines including colon cancer. Effects of lactic acid bacteria on colon cancer may vary from strain to strain and there is a need to find the new probiotic strains with tumor suppressing properties ...
background: in iran colorectal cancer (crc) incidence varies among various places. but we do not have any validate data that deeply explored the difference of crc in kerman province by national average. the aim of this study was to evaluate the incidence of colon cancer within a 12-year period in kerman province and to find whether the incidence of crc in kerman compared with the total incidenc...
Objective(s): Chemotherapies used to treat colon cancer might often fail due to the emergence of chemoresistance and side effects. Escherichia coli Nissle 1917 (EcN) is a beneficial probiotic, whose molecular mechanisms in the prevention of colon cancer are yet to be fully understood. The present study assessed the anti-cancer effects of EcN treatments in human colorec...
Introduction: Colon cancer has spread to developed countries. Probiotic bacteria can play an important role in reducing cancer and treating colon cancer. The aim of this study was to determine the effect of adjacent bovine Lactobacillus rhamnose culture on the expression of casp3 and bax genes in cancer cell. Materials & Methods: In this experimental study after bacterial culture, supernatan...
BACKGROUND Human DNA polymerase β (DNA polymerase β, polβ) is a small monomeric protein essential for short-patch base excision repair (BER). It plays an important role in regulating the sensitivity of tumor cells to chemotherapy. METHODS Luciferase reporter and western blot assays were used to determine whether polβ is a major target of miR-499. CCK-8, colony-forming survival and in vivo tum...
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