We developed several novel tools to genome wide screen for CNVs and SNPs in single cells. When applied to cleavage stage embryos from young fertile couples we discovered, unexpectedly, an extremely high incidence of chromosomal instability, a hallmark of tumorigenesis (Vanneste et al., Nature Medicine, 2009; Vanneste et al., Hum.Reprod., 2011). Not only mosaicisms for whole chromosome aneuploid...

SmallVolume 18, Issue 44 2270236 MastheadFree Access Masthead: (Small 44/2022) First published: 03 November 2022 https://doi.org/10.1002/smll.202270236AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version article.I have read accept the Wiley O...

The concept of precision agriculture emerged from the belief that variability of growing conditions is one of the major contributors to field-scale differences in yield, and that varying the agricultural inputs according to local changes in soil properties could be beneficial. Many producers have already accumulated a yield history from several growing seasons. However, to engage in an effectiv...