INTRODUCTION Imatinib mesylate (Glivec((R))/Gleevec((R))) is the standard first-line therapy for the treatment of chronic myeloid leukemia due to its high hematologic, cytogenetic, and molecular response rates and favorable long-term safety profile. A copy version of imatinib is currently available in several countries. We report on two cases of CML who were originally treated with Glivec in Eg...

OBJECTIVE To evaluate the efficacy and safety of conversion to lacosamide 400 mg/day monotherapy in adults with focal epilepsy. METHODS This historical-controlled, double-blind study (NCT00520741) enrolled patients aged 16-70 years on stable doses of 1-2 antiepileptic drugs (AEDs) and experiencing 2-40 partial-onset seizures per 28 days during the 8-week prospective Baseline. Patients were ra...

client’s recent experience with a mysterious and unexpected crash of its servers demonstrates the value of having good information. The crash caused the loss of data to that client’s critical Accounts Payable and Accounts Receivable records that kept its banker informed of the company’s financial state. After making an initial assessment of the issue, the company inquired about the use of compu...

This randomized, double-blind, placebo-controlled study assessed the safety, tolerability, and plasma-kinetic behavior of 94% pure crystalline epigallocatechin gallate (EGCG) after ten days' repeated dosing in 36 healthy male volunteers. Each of the three treatment groups consisted of 12 subjects; nine of them received oral EGCG in one dose of 200, 400, or 800 mg daily, and three received a pla...

2 Institute for Social Research, Oslo, Norway Grete Brochmann*1, Anniken Hagelund*2 Abstract During the 1990s and more so after the turn of the century, the authorities and the public in Scandinavia have become increasingly concerned about the pressure on welfare inflicted by the immigration of people with low skill levels from countries in the South. A large proportion of these newcomers have ...

Purpose – The purpose of this paper is to compare the impact of a long-term (13-week, spaced learning) with a short-term (two-day, block intensive) coaching skills training programme on participants’ coaching skills and emotional intelligence. Design/methodology/approach – In the study 23 participants completed a 13-week coaching skills training course which consisted of weekly 2.5-hour worksho...

Blood sugar levels of normal rats treated with D-400 showed significant reduction (P < 0.05) as compared to control groups. The fall was seen at one month and remained so uptill 3 months. Hyperglycemic response to adrenaline was significantly lowered (P < 0.05) following D-400 treatment. D-400 potentiated the hypoglycemia following tolbutamide treatment. Blood sugar remained persistently low in...