INTRODUCTION Magnetic resonance cholangio-pancreatography (MRCP) is a valuable method for the evaluation of biliary and pancreatic diseases and a valuable alternative to endoscopic retrograde cholangiopancreatography (ERCP). It is noninvasive and does not require the use of contrast material or ionizing radiation. Since its introduction in 1991, this technique has significantly improved in spat...

INTRODUCTION Presurgical work-ups of patients with pharmacoresistant epileptic seizures can require multiple diagnostic methods if magnetic resonance imaging (MRI) combined with video-EEG monitoring fails to show an epileptogenic lesion. Yet, the added value of available methods is not clear. In particular, only a minority of epilepsy centres apply magnetoencephalography (MEG). This study explo...

Aging alters brain structure and function and diabetes mellitus (DM) may accelerate this process. This study investigated the effects of type 2 DM on individual brain aging as well as the relationships between individual brain aging, risk factors, and functional measures. To differentiate a pattern of brain atrophy that deviates from normal brain aging, we used the novel BrainAGE approach, whic...

PURPOSE Focal radiosurgery is a common treatment modality for trigeminal neuralgia (TN), a neuropathic facial pain condition. Assessment of treatment effectiveness is primarily clinical, given the paucity of investigational tools to assess trigeminal nerve changes. Since diffusion tensor imaging (DTI) provides information on white matter microstructure, we explored the feasibility of trigeminal...

OBJECTIVES Post-traumatic intramedullary myelopathies and cavitations are well described lesions following spinal cord injury (SCI) in humans and have been described in histopathological evaluations in dogs. Human intramedullary myelopathies/cavitations are associated with severe initial SCI and deterioration of clinical signs. Canine intervertebral disc extrusions share similarities with SCI i...

Background The risk of heart failure in obesity and type 2 diabetes is greater than can be accounted for by hypertension and coronary artery disease. Rodent studies indicate that in obesity and type 2 diabetes, lipid over-storage in cardiac myocytes produces lipotoxic intermediates leading to heart failure. Cardiac steatosis was previously demonstrated in explanted hearts of patients with end-s...

Background Acute CMR imaging using late gadolinium (LGE) and T2-weighted imaging (T2W) is used to assess salvageable myocardium in STEMI patients post percutaneous coronary intervention (PCI) . However, current methods of assessing acute myocardial injury are being debated, and a more robust method would be desirable. T1-mapping quantitatively characterizes the myocardium without the need for c...

PURPOSE To develop an in-vivo imaging method for the measurement of dorsal-root-ganglia-(DRG) perfusion, to establish its normal values in patients without known peripheral nerve disorders or radicular pain syndromes and to determine the physiological spatial perfusion pattern within the DRG. METHODS This prospective study was approved by the institutional ethics committee and written informe...

BACKGROUND Based on intravascular ultrasound of the coronary arteries expansive arterial remodeling is supposed to be a feature of the vulnerable atheroslerotic plaque. However, till now little is known regarding the clinical impact of expansive remodeling of carotid lesions. Therefore, we sought to evaluate the correlation of expansive arterial remodeling of the carotid arteries with atheroscl...

Introduction. Migraine is a neurological disorder that affects up to a fifth of the population. While it is usually accepted as a frequently disabling disease, the concept that it is also associated with progressive symptoms is becoming recognized. Recent studies, including our preliminary data, have shown persistent anatomical changes in the white and in the gray matter of migraineurs, located...