نتایج جستجو برای: 396

تعداد نتایج: 3437  

2017
Mai-Juan Ma Guo-Lin Wang Benjamin Anderson Zhen-Qiang Bi Bing Lu Xian-Jun Wang Chuang-Xin Wang Shan-Hui Chen Yan-Hua Qian Shao-Xia Song Min Li John A Lednicky Teng Zhao Meng-Na Wu Wu-Chun Cao Gregory Gray

Background Our understanding of influenza A virus transmission between humans and pigs is limited. Methods Beginning in 2015, we used a One Health approach and serial sampling to prospectively study 299 swine workers and 100 controls, their 9000 pigs, and 6 pig farm environments in China for influenza A viruses (IAVs) using molecular, culture, and immunological techniques. Study participants ...

Journal: :Breast 2015
L Fallowfield S Osborne C Langridge K Monson J Kilkerr V Jenkins

BACKGROUND The 2 Cohort randomised PrefHer trial examined the preferences of HER2+ve primary breast cancer patients for intravenous (IV) or subcutaneous (SC) delivery of trastuzumab via a Single Injectable Device (SID) or hand-held syringe (HHS). The novel approach and design of the study permitted an in-depth exploration of patients' experiences, the impact that different modes of delivery had...

Journal: :Proteins 1999
J A Cuff G J Barton

A new dataset of 396 protein domains is developed and used to evaluate the performance of the protein secondary structure prediction algorithms DSC, PHD, NNSSP, and PREDATOR. The maximum theoretical Q3 accuracy for combination of these methods is shown to be 78%. A simple consensus prediction on the 396 domains, with automatically generated multiple sequence alignments gives an average Q3 predi...

2015
Yoshiaki Kawaguchi Jung-Chun Lin Yohei Kawashima Atsuko Maruno Hiroyuki Ito Masami Ogawa Tetsuya Mine

Aim. To analyze the risk factors for pancreatic stent migration, dislocation, and fracture in chronic pancreatitis patients with pancreatic strictures. Materials and Methods. Endoscopic stent placements (total 386 times) were performed in 99 chronic pancreatitis patients with pancreatic duct stenosis at our institution between April 2006 and June 2014. We retrospectively examined the frequency ...

2016
Sérgio Ferreira de Lima Mayara Mansur Fernandes Tavares Jamilly Lopes de Macedo Renata Santos de Oliveira Sandra de Andrade Heráclio Maria de Mascena Diniz Maia Paulo Roberto Eleutério de Souza Ronald Moura Sergio Crovella

Human papillomavirus (HPV) infections are strongly associated with the development of cervical intraepithelial neoplasias and invasive cervical cancer. Polymorphisms in cytokine-encoding genes and behavioural cofactors could play an important role in protecting an individual against viral infections and cancer. Here, we investigated whether IL-6 -174 G>C, IL-8 +396 G>T, and TGF-β1 +869 G>C and ...

Journal: :The Journal of biological chemistry 2003
Marc J Servant Nathalie Grandvaux Benjamin R tenOever Delphine Duguay Rongtuan Lin John Hiscott

The ubiquitously expressed latent interferon regulatory factor (IRF) 3 transcription factor is activated in response to virus infection by phosphorylation events that target a cluster of Ser/Thr residues, (382)GGASSLENTVDLHISNSHPLSLTSDQY(408) at the C-terminal end of the protein. To delineate the minimal phosphoacceptor sites required for IRF-3 activation, several point mutations were generated...

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