Background: The production of waste pollutants has become a major problem for many food and oil industries. However, oil wastes can provide alternative substrates for industry, which could help to solve environmental pollution problems. Furthermore, oil wastes can be used as substrates to produce unsaturated fatty acids, which are important for health. Objectives: The production of fatty acids ...

MMI-166 is a selective inhibitor of matrix metalloproteinase (MMP)-2 and MMP-9. Mice implanted a human colon cancer orthotopically received 200 mg/kg of MMI-166 orally for 5 weeks. Gelatin zymography demonstrated that the administration of MMI-166 remarkably decreased the active MMP-2 expression. Histological examination revealed that MMI-166 showed prominent effect on reduction of the invasive...

The development of human malignant mesothelioma (MM) is strongly associated with occupational or environmental exposure to certain natural mineral ®bers, although the genetic mechanisms underlying this malignancy remain unclear. Although the p53 gene is frequently mutated in various tumors, human asbestos-associated MMs appear to develop independently from p53 alterations. The high mesothelioma...

It has long been known from work in both Drosophila and vertebrate systems that the hedgehog signalling pathway is pivotal to embryonic development, but the past 5 years has seen an increase in our understanding of how members of this pathway are crucial to the processes of tumorigenesis. This important link was firmly established with the discovery that mutations in the gene encoding the hedge...

Inhibitory effects of 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) on the proliferation of a variety of cancer cell lines have been extensively reported. We have studied the effect of 1,25-(OH)2D3 (10 ±10 M) on the proliferation of a number of human and rat liver cancer cell lines. Additionally, the effect of 1,25-(OH)2D3 (0.02±0.5 mg/kg per day) on the rate of growth of liver cancer cell line xenog...

Substantial evidence from epidemiological studies supports the inverse association between the intake of fruits, vegetables and other plant products and cancer incidence. Cancer-preventive constituents of fruits and vegetables may inhibit carcinogen activation, enhance carcinogen detoxification, prevent carcinogens from interacting with critical target sites, or impede tumor progression. These ...

in this study, micromorphological properties of some samples collected from pedons polluted with petroleum refinery wastes and some adjacent unpolluted pedons were studied. after description of the studied pedons, disturbed and undisturbed samples were collected for physicochemical and micromorphological analyses. the results showed that the physicochemical properties (i.e. structure, bulk dens...

dental offices produce a variety of dangerous wastes during normal business day. most of these waste are non-hazardous that can be managed as household wastes; however, some component are hazardous and can pose a risk to human and the environment if discarded to municipal solid wastes. these types of wastes must be managed separately. therefore, the aim of this study was to assess the component...

I n common with most industrial processing industries, the fermentation industries are concerned with waste disposal situations that often become critical. Fermentation wastes usually occur in liquid or solid forms, although some gaseous wastes are also produced. It is worthy of note that, in addition to the problems involved, the disposal of these wastes is particularly interesting to fermenta...