نتایج جستجو برای: 3312

تعداد نتایج: 109  

2012
Lapo Alinari Courtney J. Prince Ryan B. Edwards William H. Towns Rajeswaran Mani Amy Lehman Xiaoli Zhang David Jarjoura Li Pan A. Douglas Kinghorn Michael R. Grever Robert A. Baiocchi David M. Lucas

Purpose: During cell-cycle progression, D-cyclins activate cyclin-dependent kinases (CDKs) 4/6 to inactivate Rb, permitting E2F1-mediated S-phase gene transcription. This critical pathway is typically deregulated in cancer, and novel inhibitory strategies would be effective in a variety of tumors. The protein synthesis inhibitor silvestrol has potent activity in B-cell leukemias via the mitocho...

Journal: :ACS Nano 2022

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTNano and PlantsJillian M. Buriak*Jillian Buriak*Email: [email protected]More by Jillian Buriakhttps://orcid.org/0000-0002-9567-4328, Luis Liz-Marzán*Luis Liz-Marzán*Email: Liz-Marzánhttps://orcid.org/0000-0002-6647-1353, Wolfgang J. Parak*Wolfgang Parak*Email: Parakhttps://orcid.org/0000-0003-1672-6650, Xiaodong Chen*Xiaodong Chen*Email: Chenhttps://orc...

Journal: :ACS Nano 2022

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTA New Chapter of ACS Nano: Strengthening the Impact with a Global EngagementXiaodong Chen*Xiaodong Chen*Email: [email protected]More by Xiaodong Chenhttps://orcid.org/0000-0002-3312-1664Cite this: Nano 2022, 16, 1, 1–2Publication Date (Web):January 25, 2022Publication History Published online25 January 2022Published inissue 25 2022https://doi.org/10.102...

ژورنال: :تحقیقات مهندسی سازه های آبیاری و زهکشی (تحقیقات مهندسی کشاورزی سابق) 0
حسام قدوسی عضو هیات علمی گروه مهندسی آب دانشگاه زنجان مائده اسکوهی دانشجوی کارشناسی ارشد سازه های آبی دانشگاه زنجان

هزینۀ ساخت سدهای بتنی وزنی به ­­طور معمول بیشتر از هزینۀ ساخت سدهای دیگر است و بنابراین بهینه­ سازی شکل مقطع این گونه سدها به منظور کاهش در حجم بتن مصرفی باعث اقتصادی ­تر شدن طرح می­ شود. در این پژوهش، ضمن توسعۀ مدل بهینه­ سازی جفت­ گیری زنبور عسل در محیط نرم ­افزار متلب، ابعاد سد بتنی وزنی کوینا با در نظر گرفتن شرایط پایداری بهینه شده است. برای این کار، مقطعی کلی و فراگیر به عرض واحد شامل هشت ...

Journal: :Biodiversitas 2022

Abstract. Harmonis, Rahim A, Hidayat HA, Saud OR, Wilujeng M, Sampe R, Kartika KF, Aminudin, Butar TB. 2022. Diversity of butterflies in the tropical wetland Kayan-Sembakung Delta, North Kalimantan, Indonesia. Biodiversitas 23: 3303-3312. Butterflies, which belong to order Lepidoptera, are considered superior biological indicators evaluate environmental conditions various types habitats due the...

Journal: :European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2007
Douglas West

I read with interest the article by Lim and coworkers, detailing the effect of implementation of the European Working Time Directive (EWTD) on operative training at Papworth Hospital [1]. The findings of this study are impressive, but may not reflect the wider experience of UK trainees. The Royal College of Surgeons of Edinburgh has performed nationwide surveys of the attitudes of UK and Irish ...

Journal: :Archives of internal medicine 2001
J A Baron B Y Farahmand E Weiderpass K Michaëlsson A Alberts I Persson S Ljunghall

BACKGROUND Previous studies regarding the impact of cigarette smoking on the risk of hip fracture in postmenopausal women have been inconsistent, suggesting different effects in different groups. The effect of alcohol intake on fracture risk is puzzling: moderate alcohol intake appears to increase bone density, and its association with hip fracture is not clear. METHODS To assess the associat...

Journal: :The Journal of biological chemistry 1984
D S Drust T F Martin

Thyrotropin-releasing hormone (TRH) is a tripeptide that rapidly enhances prolactin secretion in clonal, hormone-responsive GH3 rat pituitary cells. In an effort to identify postreceptor mechanisms for TRH, protein phosphorylation studies have been conducted. Our previous studies (Drust, D.S., Sutton, C.A., and Martin, T. F. J. (1982) J. Biol. Chem. 257, 3306-3312; Drust, D.S., and Martin, T. F...

2007
Douglas West

I read with interest the article by Lim and coworkers, detailing the effect of implementation of the European Working Time Directive (EWTD) on operative training at Papworth Hospital [1]. The findings of this study are impressive, but may not reflect the wider experience of UK trainees. The Royal College of Surgeons of Edinburgh has performed nationwide surveys of the attitudes of UK and Irish ...

2016
Nancy E Mayo Navaldeep Kaur Skye P Barbic Julio Fiore Ruth Barclay Lois Finch Ayse Kuspinar Miho Asano Sabrina Figueiredo Ala’ Sami Aburub Fadi Alzoubi Alaa Arafah Sorayya Askari Behtash Bakhshi Vanessa Bouchard Johanne Higgins Stanley Hum Mehmet Inceer Marie Eve Letellier Christiane Lourenco Kedar Mate Nancy M Salbach Carolina Moriello

Research in rehabilitation has grown from a rare phenomenon to a mature science and clinical trials are now common. The purpose of this study is to estimate the extent to which questions posed and methods applied in clinical trials published in Clinical Rehabilitation have evolved over three decades with respect to accepted standards of scientific rigour. Studies were identified by journal, dat...

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