An improved procedure for isolation of 5-amino-3-methyl-1,2,4-thiadiazole in pure form on a multi-gram scale without chromatography is reported. Its 1H and 13C-NMR and IR data are presented and previously published erroneous data corrected. The molecular structure is confirmed by X-ray diffraction which shows layers consisting of an elaborate two-dimensional hydrogen bonded network of molecules.

The title compound, C11H10BrNO3, is close to planar with the benzo-furan unit and the ester group subtending a dihedral angle of 5.25 (2)°. The mol-ecular structure features an intra-molecular N-H⋯O inter-action. In the crystal, N-H⋯O hydrogen bonds involving carboxyl O-atom acceptors generate a chain extending along [201].

The title compound, C(10)H(7)N(5)O(2), was synthesized by the reaction of 4-nitro-aniline and 2,3-dicyano-propionic acid ethyl ester. In the crystal, N-H⋯O and C-H⋯O hydrogen bonds link the mol-ecules, forming a three-dimensional network.

In the title compound, C(11)H(12)N(4)S, the thio-phene ring is roughly planar, with a maximum deviation of 0.012 (1) Å for the S atom, and makes a dihedral angle of 7.89 (8)° with the mean plane of the piperidine ring, which is in a chair conformation. The crystal packing is stabilized by pairs of centrosymmetric inter-molecular N-H⋯N hydrogen bonds, which results in the formation of a step-wis...

In the title compound, C(10)H(9)NO, the amino and the hydr-oxy groups act both as a single donor and a single acceptor in hydrogen bonding. In the crystal, mol-ecules are connected via chains of inter-molecular ⋯N-H⋯O-H⋯ inter-actions, forming a two-dimensional polymeric structure resembling the hydrogen-bonded mol-ecular assembly found in the crystal structure of naphthalene-1,5-diol. Within t...

In the title ammonium carboxyl-ate-carb-oxy-lic acid co-cystal, C(10)H(9)N(2) (+)·C(8)H(3)I(3)NO(4) (-.)C(8)H(4)I(3)NO(4), the carboxyl-ate anion and carb-oxy-lic acid mol-ecule are linked by O-H⋯O and N-H⋯O hydrogen bonds to form a chain running along the c axis of the monoclinic unit cell. The chains are linked by pyridinum and pyridine N-H⋯O hydrogen bonds, generating a layer motif. O-H⋯N an...

Bu çalışmada önce literatürde bulunan yöntemle maleik anhidrit (mal) ile sülfanilamitin (sa) tepkimesinden sülfanilamit içeren asit olan (E)-3-(4-sülfamoilfenilkarbamoil) akrilik (1) sentezlenmiştir. Daha sonra 1 2-amino-6-metilpiridin (2), 2-amino-5-metilpiridin (3), 2-amino-4-metilpiridin (4) ve 3-aminopiridin (5) proton transfer tuzları (6-9) elde edilmiştir. Elde edilen tuzların yapıları, e...