نتایج جستجو برای: 3 activity

تعداد نتایج: 2733570  

Journal: :Chemical and Pharmaceutical Bulletin 1981

2016
Susan J. Lindsay Yaobo Xu Steven N. Lisgo Lauren F. Harkin Andrew J. Copp Dianne Gerrelli Gavin J. Clowry Aysha Talbot Michael J. Keogh Jonathan Coxhead Mauro Santibanez-Koref Patrick F. Chinnery

Citation: Lindsay SJ, Xu Y, Lisgo SN, Harkin LF, Copp AJ, Gerrelli D, Clowry GJ, Talbot A, Keogh MJ, Coxhead J, Santibanez-Koref M and Chinnery PF (2016) HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development. Front. Neuroanat. 10:86. doi: 10.3389/fnana.2016.00086 HDBR Expression: A Unique Resource for Global and Individual Gene...

Journal: :The Journal of Cell Biology 2004
Nam-On Ku Haian Fu M. Bishr Omary

Keratins 8 and 18 (K8/18) heteropolymers may regulate cell signaling via the known K18 association with 14-3-3 proteins and 14-3-3 association with Raf-1 kinase. We characterized Raf-keratin-14-3-3 associations and show that Raf associates directly with K8, independent of Raf kinase activity or Ras-Raf interaction, and that K18 is a Raf physiologic substrate. Raf activation during oxidative and...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده علوم پایه 1389

nowadays, the development of anti cancer drugs is an important subject in pharmacology. bisphosphonates (b.p) are a great choice for design and production of the types of drugs which not only could perform as anti cancer agents but also could inhibit the function of acetyl cholinesterase (ache). ache hydrolyzes the acetylcholine (which is a neurotransmitter in nervous system) using the oh in i...

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