نتایج جستجو برای: 2r
تعداد نتایج: 4822 فیلتر نتایج به سال:
Elevated soluble interleukin-2 receptor (sIL-2R) in sera is observed in patients with malignant lymphoma (ML). Therefore, sIL-2R is commonly used as a diagnostic and prognostic marker for ML, but the mechanisms responsible for the increase in sIL-2R levels in patients with B-cell lymphomas have not yet been elucidated. We first hypothesized that lymphoma cells expressing IL-2R and some proteina...
Systemic antagonists of the histamine type 1 and 2 receptors (H1/2r) are widely used as anti-pruritics and central sedatives, but demonstrate only modest anti-inflammatory activity. Because many inflammatory dermatoses result from defects in cutaneous barrier function, and because keratinocytes express both Hr1 and Hr2, we hypothesized that H1/2r antagonists might be more effective if they were...
a valid questionnaire is a precursor to a sound measurement process. this study examined the psychometric properties of the persian version of the revised competitive state anxiety inventory – 2 (csai-2r). a total of 131 female taekwondo athletes (mean age =12.37 ± 2.52) from damghan completed csai-2r at competition venues. confirmatory factor analysis was used to analyze the structure of csai-...
The interleukin-2 receptor b chain (IL-2R b ) is expressed on a variety of hematopoietic cell types, including natural killer (NK) cells and nonconventional T lymphocyte subsets such as intestinal intraepithelial lymphocytes (IEL). However, the importance of IL-2R b -mediated signaling in the growth and development of these cells has yet to be clearly established. We have investigated IEL and N...
OBJECTIVE To evaluate the clinical significance of serum soluble IL-2R (sIL-2R) in inflammatory myopathies. METHODS Serum sIL-2R and CK levels were determined in 27 patients with IM during periods of disease exacerbation and inactive disease and were compared to 20 healthy controls and 23 controls with noninflammatory elevated CK. The performance of sIL-2R and CK tests for assessing disease a...
OBJECTIVES To date, insufficient evidence is available to recommend serum soluble interleukin-2 receptor (sIL-2R) measurement as a routine test in the assessment of sarcoidosis. Therefore, we evaluated the clinical value of this test. DESIGN Forty-seven patients with sarcoidosis, all presenting with active disease, were included in the study. Initial serum sIL-2R levels were determined by enz...
Soluble interleukin-2 receptor (sIL-2R) is a marker of T-lymphocyte activation. We have undertaken a study to examine the serum sIL-2R levels in patients with pulmonary tuberculosis (TB) and the changes following anti-TB chemotherapy. Forty four patients with pulmonary TB or tuberculous pleural effusion were recruited. Serum was collected from the patients before and at 1, 2, 4 and 6 months aft...
پپتیدها پتانسیل زیادی به عنوان دارو دارند ولی به دلایل مختلف مثل هضم توسط پروتئازها، انتقال کم از غشا و انعطاف پذیری بالا استفاده از آن ها محدودیت هایی دارد. برای جلوگیری از استفاده مقادیر بالای داروها، انتقال ویژه بافتی و کاهش اثرات جانبی آن ها، نیاز به سیستم های حامل دارورسانی احساس می گردد. بروینین- 2r ، پپتیدی 12 آمینواسیدی و یک ماده ی دفاعی غیر همولیتیک است؛ ساختاری آمفی پاتیک دارد، انت...
این پژوهش یک مطالعه مقطعی تحلیلی است.40بیمار که علائم بالینی بیماری بروسلوز را داشته و بیماری آنها با تست های سرولوژیک تأیید شده است تحت درمان آنتی بیوتیکی استاندارد به مدت 6 هفته قرار گرفتند. سطح سرمی 2me و sil-2r? قبل و بعد از درمان اندازه گیری گردید و این مقادیر با یکدیگر مقایسه شد. نتایج از میان 40 بیمار، 27 نفر(67.5%) بهبودی علائم و 13 نفر(32.5%) عدم بهبودی علائم داشتند.در مقایسه سطوح س...
This study was undertaken to determine if advanced epithelial ovarian cancer was associated with increased serum and ascitic levels of soluble interleukin-2 receptor alpha (sIL-2R alpha). Serum and ascitic fluid samples from 23 ovarian cancer patients were analyzed for sIL-2R alpha using an enzyme-linked immunosorbent assay and compared with the serum and peritoneal levels in 18 normal females....
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