Vaginal lactobacilli (VLB) spread from the mother to the infant during vaginal delivery. However, the effects of VLB on infant intestinal function remain unclear. We investigated the probiotic function and immune effects of VLB on the human embryonic intestinal epithelial cell line INT-407. VLB survived artificial gastric juice and adhered to INT-407 cells. Exposure of INT-407 cells to VLB atte...

Poloxamer 407 is a thermoreversible hydrogel frequently used as a carrier for polymer formulations in delayed-absorption drug studies, with limited toxicity in young mice. We gave six 24-month-old C57BL/6nia male mice each a subcutaneous injection of polylactic acid (PLA)/polyglycolic acid (PGA) copolymer biodegradable microparticles mixed with poloxamer 407 at a dose of 1.1 g/kg and 6 g/kg, re...

The phosphinic peptide RXP 407 has recently been identified as the first potent selective inhibitor of the N-active site (domain) of angiotensin-converting enzyme (ACE) in vitro. The aim of this study was to probe the in vivo efficacy of this new ACE inhibitor and to assess its effect on the metabolism of AcSDKP and angiotensin I. In mice infused with increasing doses of RXP 407 (0.1--30 mg/kg/...

Henle 407 and HeLa cells were compared as hosts for Shigella dysenteriae at a low multiplicity of infection. Efficiency of attachment and invasion without centrifugation, as well as selectivity for pathogenic over nonpathogenic S. dysenteriae without Congo red, were much greater for Henle 407 cells than for HeLa cells.

V407 Vul (= RXJ1914.4+2457) shows pulsations in X-ray flux on a period of 9.5 minutes, which have been ascribed to accretion onto a magnetic white dwarf, with the X-ray pulses seen as the accreting pole moves into and out of view. The X-ray flux drops to zero between pulses, and no other periods are seen, suggesting that V407 Vul is a type of system known as a “polar” in which the white dwarf h...

       The purpose of this study was to investigate the effect of additives, poly(ethylene glycol) (PEG) 1450, poloxamer 407, polyvinyl alcohol (PVA) and sodium chloride in order to improve physico-chemical characteristics, encapsulation efficiency and in vitro release of bovine serum albumin, form poly(D,L-lactic-co-glycolic acid) (PLGA) microparticles prepared by the w/o/w solvent evaporation...

We report on the formation of surface instabilities in a layer of thermoreversible ferrogel when exposed to a vertical magnetic field. Both static and time dependent magnetic fields are employed. Under variations of temperature, the viscoelastic properties of our soft magnetic matter can be tuned. Stress relaxation experiments unveil a stretched exponential scaling of the shear modulus, with an...