Extended-spectrum -lactamases (ESBLs), such as the plasmid-mediated class A TEMand SHV-type enzymes, have developed by stepwise mutations in their structural genes, resulting in either single or multiple amino acid changes in the encoded enzymes, and these changes sufficiently remodel the active site to allow attack on aminothiazolyl compounds. Since they were first identified at the beginning ...

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Background Psoriatic arthritis (PsA) is a chronic inflammatory that develops in at least 5% of patients with psoriasis. It affects women and men equally. Obesity, diabetes, hypertension hypercholesterolemia always affect PsA patients. Objectives To study the gender race effect on prevalence metabolic comorbidities among Malaysia. Methods This restrospective study. The medical records all under ...

BopE is a type III secreted protein from Burkholderia pseudomallei, the aetiological agent of melioidosis, a severe emerging infection. BopE is a GEF (guanine-nucleotide-exchange factor) for the Rho GTPases Cdc42 (cell division cycle 42) and Rac1. We have determined the structure of BopE catalytic domain (amino acids 78-261) by NMR spectroscopy and it shows that BopE(78-261) comprises two three...

The thermal decomposition of the complexes: [Fe(C17H2404)[.5-2H20]n and [UO2(C17H2404"2H20]n, and evaluation of kinetic parameters (E, Z and AS ) by making use of Piloyan-Novikova, Coats-Redfern and Horowitz-Metzger equations are reported. The complexes are found to decompose in three well defined steps involving random nucleation mechanism. The intermediates formed during decomposition usually...

 ABSTRACTBackground: 226 Ra and 228 Ra contents in foodstuffs of Ramsar which is a coastal city in the northern part of Iran were determined by gamma spectrometry. Measurement results together with food consumption rates were used to estimate annual effective dose from  226 Ra and 228 Ra, due to consumption of food stuffs by inhabitants of Ramsar city.Materials and Methods: A total of 33 sample...

Background: Minimally invasive surgeries, such as laparoscopic and robotic have been the main treatment methods for stage I endometrial cancer instead of laparotomy. However, minimally surgeries malignant tumors not yet established in many rural hospitals or with few gynecologists. This study aimed to investigate whether surgery is more sustainable useful at a hospital where single non-laparosc...