A new benzofuroquinoline derivative, 3,9-bis(N,N-dimethylcarbamoyloxy)-5H-benzofuro[3,2-c]quinoli ne-6-one (KCA-098), shows poor oral absorption due to practical insolubility in water. In this study, a co-grinding technique employing a water-soluble polymer was used for improvement of the dissolution rate of KCA-098. Powder X-ray diffraction patterns and IR spectra of KCA-098 showed the convers...

background: gastric lavage (gl) is one of the most commonly used decontamination method for cholinergic insecticide ingestion in developing countries despite lack of supporting evidence. this study was designed to evaluate the outcome of patients with cholinergic insecticide poisoning treated with gl in regards to timing and frequency of the procedure. methods: in this prospective observational...

BACKGROUND Data available on the effect of quality (glycemic index [GI]) and quantity (glycemic load [GL]) of carbohydrates on the risk factors of cardiovascular disease (CVD) are inconsistent. The objective of this study was to examine the association between dietary GI, GL, and CVD risk factors among Tehranian adults, the participants of the Tehran Lipid and Glucose Study. METHODS This popu...

Although many epidemiological studies have examined the association of dietary glycaemic index (GI) and glycaemic load (GL) with health outcomes, information on the reproducibility and relative validity of these variables estimated from dietary questionnaires is extremely limited. We examined the reproducibility and relative validity of dietary GI and GL assessed with a self-administered diet-h...

The aims of this study were to elucidate the immunomodulatory effects of glycyrrhizin (GL) on CD4(+)T cell responses during liver fibrogenesis. To obtain in vivo evidence about the effects of GL on CD4(+)T cells in livers and spleens of concanavalin A (ConA)-induced mouse model, mice were administrated with ConA together with or without GL for 8 weeks. Mice treated with GL dramatically prevente...

This work concerns linear multiplicity free actions of the complex groups GC = GL(n,C), GL(n,C) × GL(n,C) and GL(2n,C) on the vector spaces V = Sym(n,C), Mn(C) and Skew(2n,C). We relate the canonical invariants in C[V ⊕ V ∗] to spherical functions for Riemannian symmetric pairs (G,K) where G = GL(n,R), GL(n,C) or GL(n,H) respectively. These in turn can be expressed using three families of class...

background and objectives: preparation and evaluation of nanocomposite films have become prevalent in recent years. depending on the purpose of using the film, and considering the effects and interaction effects of nanomaterial and other modifiers on the film properties, the amounts of nanomaterials and modifiers should be optimized. the effects of montmorillonite (mmt), glycerol (gl), and thei...