Iraq is suffering from depleted uranium (DU) pollution in many regions and the effects of this may harm public health through poisoning and increased incidence of various cancers and birth defects. DU is a known carcinogenic agent. About 1200 tonnes of ammunition were dropped on Iraq during the Gulf Wars of 1991 and 2003. As a result, contamination occurred in more than 350 sites in Iraq. Curre...

PURPOSE Histone deacetylase 5 (HDAC5) is an important protein in neural and cardiac diseases and a potential drug target. However, little is known regarding the specific role of HDAC5 in breast cancer (BC). We aimed to evaluate HDAC5 expression in human breast tumors and to determine the effects of the inhibition of HDAC5 expression in BC cells. EXPERIMENTAL DESIGN HDAC5 expression was evalua...

AMA Güneş A, Tekin Y, El Ç, Bektaş H. THE EFFECT OF AN EDUCATIONAL VIDEO ON PATIENTS' BOWEL PREPARATION BEFORE COLONOSCOPY: A SINGLE-BLIND RANDOMIZED CONTROLLED STUDY. Health Problems of Civilization. 2023;17(3):226-235. doi:10.5114/hpc.2023.130496. APA Güneş, A., Tekin, Y., El, Ç., & Bektaş, (2023). Civilization, 17(3), 226-235. https://doi.org/10.5114/hpc.2023.130496 Chicago Ayşegül, Yasemin ...

Herrera, AF.* and Penteado-Dias, AM.* aPrograma de Pós-Graduação em Ecologia e Recursos Naturais, Universidade Federal de São Carlos – UFSCar, Rod. Washington Luís, Km 235, CEP 13565-905, São Carlos, SP, Brazil bDepartamento de Ecologia e Biologia Evolutiva, Universidade Federal de São Carlos – UFSCar, Rod. Washington Luís, Km 235, CEP 13565-905, São Carlos, SP, Brazil *e-mail: andresfhf@gmail....

Bruno A. Marichal-Cancino1, Carlos M. Villalon1 1Department of Pharmacobiology, Cinvestav Coapa, Czda. Tenorios 235, Col. Granjas-Coapa, Deleg. Tlalpan, 14330 Mexico DF, Mexico. Corresponding Author: Bruno A. Marichal-Cancino, Department of Pharmacobiology, Cinvestav Coapa, Czda. Tenorios 235, Col. Granjas-Coapa, Deleg. Tlalpan, 14330 Mexico DF, Mexico, Tel: 52-55-5483 2854; Email: br.marichal@...

# Author for correspondence: Nahuel Fittipaldi, Ph.D. Public Health Ontario, Toronto Laboratories, 81 17 Resources Rd, Toronto, Ontario M9P 3T1, Canada. Phone: (416) 235-5714. Fax: (416) 235-6063. E-mail: 18 [email protected]. 19 JCM Accepts, published online ahead of print on 19 February 2014 J. Clin. Microbiol. doi:10.1128/JCM.03554-13 Copyright © 2014, American Society for Microbiol...

Cancer stem cells (CSCs) play major roles in cancer initiation, progression, and metastasis. It is evident from growing reports that PI3K/Akt/mTOR and Sonic Hedgehog (Shh) signaling pathways are aberrantly reactivated in pancreatic CSCs. Here, we examined the efficacy of combining NVP-LDE-225 (PI3K/mTOR inhibitor) and NVP-BEZ-235 (Smoothened inhibitor) on pancreatic CSCs characteristics, microR...

Oxytocin antagonist (OTA), TT-235, was developed by our group and shown to inhibit either spontaneous or oxytocin-induced uterine contractions in primates. The purpose of the present study was to confirm the duration of TT-235 to block oxytocin-induced uterine contractions in estrous rats. In Experiment 1, the time-response of the three OTAs on uterine contractility was examined. The rats were ...