In the present study, use of MgFe2O4@SiO2-SO3H as an efficient, green, magnetically recoverable & recyclable catalyst for micro-wave assisted solvent free synthesis 2,3-dihydroquinazolin-4(1H)-ones reaction pathway is presented. The superiorities this method are higher conversion rate, shorter time, easy isolation product and reusability without remarkable loss activity. synthesized derivatives...

Certain monoclonal antibodies (MoAbs) specific for platelet membrane glycoproteins are known to be capable of activating platelets, and it is generally thought that platelets from normal subjects are equally susceptible to stimulation by such MoAbs. We found that platelets from 20 normal donors varied significantly in their sensitivity to three IgG1 murine MoAbs specific for membrane glycoprote...

We reported previously (±)-2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one [(±)-Retro-2(cycl)] as the chemical structure of Retro-2 that showed mouse protection against ricin, a notorious ribosome inactivating protein (RIP). Herein we report our chemical resolution of (±)-Retro-2(cycl), analog synthesis, and cell-based evaluation showing that the two optically pure enantiomer...

In this paper, magnetic chitosan is used as a support for the immobilization of copper catalyst (Cu@MChit). The fabricated successfully synthesized and characterized by several techniques. activity Cu@MChit evaluated in synthesis novel derivatives 3-alkyl-2-arylthio-2,3-dihydroquinazolin-4(1H)-ones. products are three simple steps via Chan–Lam coupling reaction. synthetic route based on reactio...

A novel and cost-effective catalyst for synthesis of 2,3'-dihydroquinazolin-4-(1H)-ones was developed utilizing a combined nanocomposite obtained from bonding TiCl3 to hydroxyl groups of nanofibrillated cellulose as a green and inexpensive support.The structure of the catalyst was investigated using the Fourier transform infrared spectroscopy (FT-IR), field emission scanning...