نتایج جستجو برای: 211
تعداد نتایج: 8534 فیلتر نتایج به سال:
Purpose: To assess the effects of ligustrazine on progression hypoxia-reoxygenation (H/R), and explore possible role miR-211 in myocardial ischemia-reperfusion (I/R) injury identify its potential targeting gene. Methods: The level H/R-induced cells was detected by quantitative polymerase chain reaction. CCK-8, flow cytometry (FCM), Western blot assays were performed to examine effect USP47 remi...
The non-coding microRNAs (miRNA) have tissue- and disease-specific expression patterns. They down-regulate target mRNAs, which likely impacts on most fundamental cellular processes. Differential expression patterns of miRNAs are currently being exploited for identification of biomarkers for early disease diagnosis, prediction of progression for melanoma and other cancers and as promising drug t...
MiR-204 and 211 enforced expression in murine mesenchymal stromal cells (MSCs) has been shown to induce adipogenesis and impair osteogenesis, through RUNX2 down-modulation. This mechanism has been suggested to play a role in osteoporosis associated with obesity. However, two further fundamental MSC functions, chondrogenesis and hematopoietic supporting activity, have not yet been explored. To t...
The 10% amplitude calibration accuracy achievable with the current standard calibration techniques may be suucient to produce images with dynamic range of 10 3 , but achieving a dynamic range of 10 4 or higher with the MMA requires better than 1 percent accuracy in amplitude calibration. A self-calibration technique may be applied to improve images, but it may not be possible in all cases. Ther...
Cannabinoids (CBs) show promise as neuroprotectants with some agents already licensed in humans for other conditions. We systematically reviewed CBs in preclinical stroke to guide further experimental protocols. We selected controlled studies assessing acute administration of CBs for experimental stroke, identified through systematic searches. Data were extracted on lesion volume, outcome and q...
Spinal cord injury (SCI) makes a major contribution to disability and deaths worldwide. Reactive astrogliosis, a typical feature after SCI, which undergoes varying molecular and morphological changes, is ubiquitous but poorly understood. Reactive astrogliosis contributes to glial scar formation that impedes axonal regeneration. Brain-derived neurotrophic factor (BDNF), a well-established neurot...
Adult T-cell leukemia (ATL) consists of an overabundance of T cells, which express CD25. Therapeutic efficacy of astatine-211 ((211)At)-labeled murine monoclonal antibody 7G7/B6 alone and in combination with daclizumab was evaluated in nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice given injections of MET-1 human T-cell leukemia cells. Daclizumab and 7G7/B6 are directed towa...
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