Numerous studies, mostly case reports, have found that occupational exposure to coal tars or coal-tar pitches (coal-tar distillates) is associated with skin cancer, including scrotal cancer; workers in these studies have included patent-fuel (coal-briquette) workers, pitch loaders, workers in electrical trades, and optical-lens polishers (IARC 1985, 1987). A 1946 study in the United Kingdom fou...

In recent years, there has been a growing interest in teichoic acids as targets for antibiotic drug design against major clinical pathogens such as Staphylococcus aureus, reflecting the disquieting increase in antibiotic resistance and the historical success of bacterial cell wall components as drug targets. It is now becoming clear that β-O-GlcNAcylation of S. aureus wall teichoic acids plays ...

Relational DBMSs have been shown to be inefficient for scientific data management. One main reason is the difficulty to represent arrays, which are frequently adopted as a data model for scientific datasets representation. Array DBMSs, e.g. SciDB, were proposed to bridge this gap, building on a native array representation. Unfortunately, important scientific applications, such as numerical simu...

Biomass can be considered a renewable energy source. It undergoes gasification process to obtain gaseous fuel, which converts it into combustible products such as hydrogen, carbon monoxide, and methane. The also generates undesirable tars that condense in gas lines cause corrosion, after processing, an additional source of gases. This study focused on the processing tar substances with toluene ...

Aminoacyl-tRNA synthetases (AARSs) catalyze an early step in protein synthesis, but also regulate diverse physiological processes in animal cells. These include angiogenesis, and human threonyl-tRNA synthetase (TARS) represents a potent pro-angiogenic AARS. Angiogenesis stimulation can be blocked by the macrolide antibiotic borrelidin (BN), which exhibits a broad spectrum toxicity that has disc...

Introduction: Eolian sedimentary deposits are important because they provide a record of the direction and strength of winds on Mars and the type and flux of sediments transported by the winds. While Martian sand dunes and transverse aeolian ridges ("TARs") have been thoroughly studied, the sedimentary deposits left behind by blowing dust have received comparatively little attention to date. Wi...