In addition to four previously reported compounds: proximadiol (1), 5α-hydroxy-β-eudesmol (2), 1β-hydroxy-β-eudesmol (4) and 1β-hydroxy-α-eudesmol (5), two new sesquiterpenes, 5α-hydroperoxy-β-eudesmol (3) and 7α,11-dihydroxycadin-10(14)-ene (6) were isolated from the unsaponifiable fraction of the petroleum ether extract of Cymbopogon proximus STAPF. Isolation of compounds 2, 4 and 5 from the ...

An efficient synthesis of the 1-hydroxy-2-(prop-2'-enyl)9-anthrone is described. Selective nitration of anthraquinone, reduction to the corresponding amine, diazotization and treatment by sulfuric acid solution afforded the 1-hydroxy-9,10-anthraquinone in good yield as the key intermediate. Reaction with allyl bromide/K2CO3 and subsequent selective reduction accompanie...

A new molecule of 2-[3, 4 di hydroxy phenyl] 3, 5, 14-trihydroxy 13oxo 2H-chromeno [34:5, 6] pyrano [2, 3-h] 4H-chromene 4-one was synthesized and screened. This new compound was synthesized by incorporating 4-chloro-3-formyl coumarin group with quercetin compound. In the present study the antioxidant and antimalarial activities of new 2-[3, 4 di hydroxy phenyl] 3, 5, 14-trihydroxy 13oxo 2H-chr...

A Beijerinckia strain designated strain B1 was shown to oxidize benz[a]anthracene after induction with biphenyl, m-xylene, and salicylate. Biotransformation experiments showed that after 14 h a maximum of 56% of the benz[a]anthracene was converted to an isomeric mixture of three o-hydroxypolyaromatic acids. Nuclear magnetic resonance and mass spectral analyses led to the identification of the m...

Skimmia laureola Hook (Rutaceae) is found in Kashmir and in the mountains of Northern Pakistan and is used in folklore medicine for the treatment of various ailments [1 – 3]. The quinoline alkaloids of this plant have demonstrated antifungal and immunomodulating properties [4, 5]. The ethanolic extracts of the aerial parts of S. laureola are active against the animal pathogen Microsporium canis...

Two new bisabolane-type sesquiterpenoids, (3R,4R,6S)-3,4-epoxybisabola-7(14),10-dien-2-one and (1R,3R,4R,5S,6S)-1-acetoxy-8-angeloyloxy-3,4-epoxy-5-hydroxybisabola-7(14),10-dien-2-one, and a new oplopane-type sesquiterpenoid, 14(R)-hydroxy-7beta-isovaleroyloxyoplop-8(10)-en-2-one, were isolated from Farfarae Flos along with three known compounds. The structures of these compounds were elucidate...