The aim of this study was to investigate the effects of edaravone on lung injury caused by myocardial ischemia reperfusion (I/R) in rats. Wistar rats (n=24) were randomly divided into 4 groups: the sham operation (S group) and myocardial I/R groups (C group) and two edaravone‑treated groups (E1 and E2 groups). Rats in the E1 and E2 groups were injected with 3 or 10 mg/kg edaravone, respectively...

Strain-induced quenching of optical transitions has been found in capped self-assembled quantum dot structures. Light absorption at the E1 and E1 1 D1 critical points of InSb islands buried in InP disappears for nominal InSb thicknesses lower than 10 monolayers as a consequence of the strain produced inside the islands by the cap layer. Certainly, this strain increases as the InSb deposition di...

knowing that adenoviral vectors could initiate innate immunity, the ability of e1-deleted recombinant adenovirus (ad-e1δ) in induction of b7.1 and il-2 molecules was studied. methods: the expression of green fluorescent protein in c1498 cells following transfection of these cells with adenovirus green fluorescent protein vector confirmed the ability of adenovirus vectors in infecting the cells ...

Let κ be an inaccessible cardinal, and let E0 = {x ∈ Pκκ + : cf λx = cf κx} and E1 = {x ∈ Pκκ : κx is regular and λx = κ + x }. It is consistent that the set E1 is stationary and that every stationary subset of E0 reflects at almost every a ∈ E1. Supported by NSF grants DMS-9401275 and DMS 97-04477. Typeset by AMS-TEX 1 2 THOMAS JECH AND SAHARON SHELAH

For the RuIII/II couple in [(bpy)2ClOs(4,4′-bpy)Ru(NH3)5] (bpy ) 2,2′-bipyridine; 4,4′-bpy ) 4,4′bipyridine), E1/2 varies linearly with the donor number (DN) of the solvent with a slope of -26 ( 3 mV/DN unit ranging from nitromethane to dimethyl sulfoxide. For the OsIII/II couple, the variation is -3 ( 1 mV/DN unit. Plots of ∆E1/2 ) E1/2(2) E1/2(1) vs DN (E1/2 is the half wave potential for the...

BACKGROUND scoliosis correction surgery is common in children, and adolescents. Deliberate hypotension is indicated in scoliosis correction procedures, because bloodless field is needed for exposure of the nerve roots, and to decrease the need for blood transfusion. Protection of the kidneys during deliberate hypotension is essential. The ideal hypotensive drug maintains the renal function and ...

We have performed microsecond molecular dynamics (MD) simulations and protein pKa calculations of the muscle calcium pump (sarcoplasmic reticulum Ca(2+)-ATPase, SERCA) in complex with sarcolipin (SLN) to determine the mechanism by which SLN inhibits SERCA. SLN and its close analog phospholamban (PLN) are membrane proteins that regulate SERCA by inhibiting Ca(2+) transport in skeletal and cardia...

Let , m , n , r be integers such that 2 ≤ ≤ r , r ≥ 4 and m , n ≥ 0 . Suppose G is an r -regular -edge-connected graph and that k is an even integer with m ≤ k ≤ r 2 . We say that G is an (m,n; k) -factor graph if for each disjoint pair E1, E2 ⊆ E(G) with |E1| = m and |E2| = n , G has a k -factor F such that E1 ⊆ E(F ) and E2 ∩E(F ) = ∅ . In this note we consider when G is an (m,n; k) -factor g...

Post-translational modifications by ubiquitin-like proteins are among the most important mechanisms for regulating a wide variety of cellular functions. In these modifications an E1 enzyme activates each ubiquitin-like protein (Ubl) by adenylation of the Ubl C-terminal COOH group and then forms a thioester bond with the adenylated C-terminal COOH group of the Ubl. Previous x-ray crystallography...