The interaction between propranolol (PROP) and human serum albumin (HSA) was studied in the presence of dimethyl methylphosphonate (DMMP). DMMP is usually considered as a simulant for chemical warfare agents (CWAs). For this purpose fluorescence quenching, resonance light scattering (RLS), synchronous, three-dimensional fluorescence spectroscopy and molecular dynamics (MD) simulation were emplo...

Sulfur mustard (SM) is a bifunctional alkylating agent with a long history of use as a chemical weapon. Although its last military use is dated for the eighties of the last century, a potential use in terroristic attacks against civilians remains a significant threat. Thus, improving medical therapy of mustard exposed individuals is still of particular interest. PARP inhibitors were recently br...

A 2-chloroethyl ethyl sulfide (2-CEES) gas sensor based on WO 3 /graphite nanocomposite with high selectivity and fast response-recovery properties was successfully developed.

A number of recent terrorist attacks make it clear that rapid response, high sensitivity and stability are essential in the development chemical sensors for detection warfare agents. Nerve agent sarin [2-(fluoro-methyl-phosphoryl) oxypropane] is an organophosphate (OP) compound recognized as one most toxic Considering sarin’s toxicity, being odorless colorless, dimethyl methylphosphonate (DMMP)...

The photooxidation of a mustard-gas simulant, 2-chloroethyl ethyl sulfide (CEES), is studied using a porphyrin-based metal-organic framework (MOF) catalyst. At room temperature and neutral pH value, singlet oxygen is generated by PCN-222/MOF-545 using an inexpensive and commercially available light-emitting diode. The singlet oxygen produced by PCN-222/MOF-545 selectively oxidizes CEES to the c...

In this work, the practicality of catalytic surfaces of nano-structured Co3O4 and MnCo2O4 for the adsorption and neutralization reactions of dimethyl methyl phosphonate (DMMP) as an toxic agricultural organo-phosphorous pesticide has been investigated. The Co3O4 and MnCo2O4 NPs have been successfully prepared by precipitation method using cobalt nitrate and manganese nitrate as the precursors a...

A polymer-coated surface acoustic wave (SAW)-based chemical sensor for organophosphorous compound sensing at extremely low concentrations was developed, in which a dual-delay-line oscillator coated with fluoroalcoholpolysiloxane (SXFA) acted as the sensor element. Response mechanism analysis was performed on the SXFA-coated chemical sensor, resulting in the optimal design parameters. The shear ...

mnco2o4 (mno-co2o3) nanocomposite as a binary oxide has been successfully prepared by precipitation method using cobalt nitrate and manganese nitrate as the precursors and then characterized by scanning electron microscopy-energy dispersive micro-analysis (sem-edx) and x-ray diffraction (xrd) techniques. in this work, we report the hydrolysis kinetics reactions of semi mustard (chloroethyl ethy...

Flower-like WO(3) particles with high specific surface area were synthesized via a template/surfactant-free way. Scanning and transmission microscopies and X-ray diffraction were applied to investigate the formation mechanism of the morphology. Gas sensing characterization showed an enhanced sensitivity (70 Hz/ppm) to dimethyl methylphosphonate (DMMP) as compared with previously reported WO(3) ...

MnCo2O4 (MnO-Co2O3) nanocomposite as a binary oxide has been successfully prepared by precipitation method using cobalt nitrate and manganese nitrate as the precursors and then characterized by scanning electron microscopy-energy dispersive micro-analysis (SEM-EDX) and X-ray diffraction (XRD) techniques. In this work, we report the hydrolysis kinetics reactions of semi mustard (chloroethyl ethy...