نتایج جستجو برای: 2 aryl 1 arylmethyl 1h benzimidazoles

تعداد نتایج: 3951906  

1-Methyl-3-(2-oxyethyl)-1H-Imidazol-3-ium-Borate Sulfonic Acid ([MOEI]-BSA) was easily prepared and used as a new and highly efficient solid acid catalyst for the synthesis of benzimidazole derivatives with high isolated yields. Various substituted benzimidazoles were synthesized by a combination of o-phenylenediamines and aldehydes in the presence of [MOEI]-BSA with excellent yields in water a...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد یزد - دانشکده شیمی 1393

واکنش های تک ظرفی دو مینو، آریل آمین ها، آلکیل پروپیولات ها، ایزاتین و ایندول در حلال اتانول و در دمای اتاق با استفاده از fecl3 به عنوان کاتالیزور مورد بررسی قرار گرفت، که منجر به تشکیل محصول 2-(2-oxo-1,2-dihydro-1h-[3,3]biindolyl-3-yl)-3-aryl amine-acrylic acid alkyl ester با راندمان بالا گردید.

Journal: :journal of pharmaceutical and health sciences 0

a simple, fast, efficient and environmentally friendly method for synthesis of benzimidazole and its 2-alkyl, aryl and heteroaryl substituted derivatives was developed using zeolite hy. two component cyclolcondensation of 1,2-phenylenediamine (o-phenylenediamine) and commercially available carboxylic acids catalyzed by zeolite hy without any solvent, under microwave irradiation led to formation...

Journal: :Inorganics (Basel) 2023

An overview of the known methods introducing selenium under action elemental into structures various saturated, unsaturated, and heteroaromatic selenacycles containing C–Se, N–Se, B–Se, Ge–Se P–Se bonds is presented. These include metal, iodine, bromine or chlorine exchange for direct cyclization 1-(2-bromoaryl)benzimidazoles, polyunsaturated hydrocarbons, acetylenes, propargylic amines, 3-halo...

2013
Vyankat A. Sontakke Sougata Ghosh Pravin P. Lawande Balu A. Chopade Vaishali S. Shinde

A new, efficient method for the synthesis of 2-aryl substituted benzimidazole by using silica supported periodic acid (H5IO6-SiO2) as a catalyst has been developed. The salient feature of the present method includes mild reaction condition, short reaction time, high yield and easy workup procedure. The synthesized benzimidazoles exhibited potent anticancer activity against MCF7 and HL60 cell li...

2011
Deepak K Aneja Poonam Lohan Sanjiv Arora Chetan Sharma Kamal R Aneja Om Prakash

BACKGROUND Thiazolidine-2, 4-diones (TZDs) have become a pharmacologically important class of heterocyclic compounds since their introduction in the form of glitazones into the clinical use for the treatment of type 2 diabetes. TZDs lower the plasma glucose levels by acting as ligands for gamma peroxisome proliferators-activated receptors. In addition, this class of heterocyclic compounds posse...

Journal: :The Journal of organic chemistry 2007
Liangbo Zhu Peng Guo Gaocan Li Jingbo Lan Rugang Xie Jingsong You

Relatively mild and highly efficient CuI-catalyzed N-arylation procedures for nitrogen-containing heterocycles (e.g., imidazoles, benzimidazoles, pyrroles, pyrazoles, indoles, triazoles, etc.) with aryl and heteroaryl halides have been developed. The protocols can be performed easily and tolerate a number of functional groups, such as ester, nitrile, nitro, ketone, free hydroxyl, and free prima...

Journal: :Organic & biomolecular chemistry 2010
Varun Kumar Pallepogu Raghavaiah Shaikh M Mobin Vipin A Nair

Diastereoselective syntheses of 3-aryl-(S/R)-6-methyl-1-[(S/R)-1-phenylethyl)]-2-thioxotetrahydro pyrimidin-4(1H)-ones were achieved in good yields by the condensation of aryl isothiocyanates with ethyl 3-(1-phenylethylamino)butanoate in a one-pot reaction. Benzylation of these substrates illustrated that the orientations of the exocylic and endocylic groups determine the stereochemical outcome...

2013
ANJU GOYAL NEELAM JAIN

A series of 1-phenyl-3-aryl-5-(4-(3-propanoloxy) phenyl)-1H-pyrazoles were synthesized from chalcones and studied for their in vitro antibacterial activity. Chalcones i.e.,1-aryl-3-(4hydroxyphenyl) prop-2-en-1-ones (1) on reaction with phenyl hydrazine in presence of acetic acid and few drops of HCl yielded the corresponding 1-phenyl-3-aryl-5-(4-hydroxyphenyl)-1H-pyrazoles (2) which on further ...

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