Through this study, a group of heterocyclic compounds represented by five-membered ring, seven rings, and tetracyclic Oxazepine, β-lactam, Thiazolidines, Imidazolidines, were prepared depending on the intermediate compound, Schiff bases, that from reaction 2-Aminobenzimidazol with 4-Bromobenzaldehyde to form (azomethine-CH=N) above formed pathway bond. All new derivatives created Fourier Transf...

The research included the preparation of two Schiff bases MA1,2 starting from1-methyl-pyrazole-4-carbaldehyde with 4-chloroaniline or 4-amino antipyrine in equal moles presence glacial acetic acid. Then xazepane rings MA (3-6) were prepared from phthalic anhydride maleic anhydride. chemical formulas confirmed using FTIR, 1HNMR, and 13CNMR spectroscopy. toxicity activity compound MA2 against bre...

Objective: Synthesis and evaluation of anti-inflammatory activity of some novel 7-azaisatin derivatives. Methods: Novel Schiff bases of 7-azaisatin (VI) were synthesized by condensation of ethyl-2-(1-benzyl-2-oxo-1,2-dihydro-3H-pyrrolo[2,3b]pyridin-3-ylidene) hydrazine carboxylate (V) with various primary amines. The compound (V) was synthesized by reacting ethylchloroformate with 1-benzyl7azai...

New coordination complexes of Co, Ni and Zn with Schiff base N’-((2-thioxo-1,2-dihydroquinoline-3yl)methylene) pyridine-4-carbohydrazide have been synthesized and characterized by several techniques using elemental analysis (C, H, N), IR spectra and 1HNMR spectra. The new Schiff base has been synthesized by the reaction of pyridine-4-carbohydrazide and 2-thioxo-1,2dihydroquinoline-3-carbaldehyd...

A metabonomics method using (1)H nuclear magnetic resonance spectroscopy ((1)HNMR) was applied to obtain a systematic view of the development and progression of postmenopausal osteoporosis. Using partial least squares discriminant analysis (PLS-DA), 26 and 34 characteristic resonances were found respectively in urine and plasma of ovariectomized rats (Variable importance, VIP value ≥1.0), and t...

In this paper, two of the new antipyrine heterocyclic derivatives have been synthesized via formation Schiff bases. The bases compounds were generated from reaction 4-Ameno-antipyrine (4-AAP) with 3- hydroxybenzaldehyde and 4- nitrobenzaldehyde, which was converted to imidazolidinone by glycine. reactions monitored Thin Layer Chromatography (TLC). structure prepared confirmed physical available...

Synthesis of 2-(4-Acetyl-phenyl)-4-nitro-isoindole-1, 3-dione chalcones were performed by fusion 3-nitro phthalic anhydride with p-aminoacetophenone. Then the later was grinded different aromatic aldehydes in presence sodium hydroxide to produce new derivatives A3-10 without using any solvent formation N-arylphthailimide confirmed FTIR,1HNMR, 13CNMR spectroscopy and all final compounds tested f...

copper (ii) phthalocyanine and 2,9,16,23 tetrakis nitro copper (ii) phthalocyaninehas been synthesized respectively from phthalonitrile and 4-nitro phthalonitrile under solvent-free condition using two different catalystsovernanodimensionalzeolites. 4-nitro phthalonitrile synthesized from phthalimide in three steps. the newly prepared compounds have been characterized by ir, uv-vis, 1hnmr and m...