miR (microRNA)-192 plays key roles in renal pathological and physiological responses, by repressing targets including Zeb1, Zeb2 and Wnk1. In the present study, we have assessed the regulation of miR-192 expression. We found that TGF-β1 (transforming growth factor β1) down-regulates miR-192 and miR-194, co-transcribed in the shared precursor pri-miR (primary miR transcript)-192/194. Luciferase ...

BACKGROUND The neck region contains a high density of vital organ structures within a relatively small and unprotected anatomic region, making it one of the most vulnerable areas of the body for all types of injuries. OBJECTIVES In this article, we studied penetrating neck trauma cases in Alzahra Hospital over a 10-year period. PATIENTS AND METHODS In this retrospective, descriptive, analyt...

Student engagement is considered an important predictor of student achievement, but few researchers have attempted to derive a valid and reliable measure of college student engagement in particular courses. In 2 studies, we developed and explored the validity of a measure of student engagement, the Student Course Engagement Questionnaire (SCEQ). Exploratory factor analysis revealed 4 dimensions...

A method for the ratiometric pH sensing using LysoSensor DND-192 is presented in this paper. It works in the physiological pH range. It is based on the use of two fluorophores which differ significantly in their lifetimes. As the discrimination of their emissions is performed through two different frequencies, this method can allow significant overlap of the emission spectra. A simple long-pass...

Curcumin is the main active ingredient extracted from the traditional Chinese medicine, turmeric, which acts against non-small cell lung cancer cell (NSCLC), lowers blood pressure, is anti-inflammatory, choleretic, and exerts anti‑oxidant effects, without any obvious toxicity in the long term. The aim of the present study was to investigate whether the anticancer effect of curcumin inhibited ce...

SEED is a 128-bit block cipher with a 128-bit secret key. Since it supports only a 128-bit secret key, it is difficult to apply this algorithm to various environments. In this paper, we propose SEED192/256 which support 192/256-bit secret keys, respectively. Also we evaluate the security these algorithms against well-known attacks and the software performance of them on PC environments.

The author investigates Russian federalism and the constitutional underpinnings of the power vertical, looking specifically at the Constitutional Court’s December 2005 case about the appointment of governors. The court’s decision upheld the constitutional notion of a “unified system of executive power” as the primary legal justification for the power vertical. However, not all of the justices a...