Positron emission tomography (PET) using the radiolabeled glucose analogue 18F-FDG allows uncovering glycolysis processes within cancer cells and reveals high value in diagnosis, staging, relapse and therapeutic response evaluation in several malignancies. Breast cancer presents considerable variability when it comes to 18F-FDG uptake, which results in different sensitivity and specificity valu...

In combined PET/CT imaging, functional data provided by 18FFDG increase diagnostic accuracy over conventional PET and CT in a variety of malignancies. The question to be raised is: how much is CT needed in PET/CT imaging? Discussion: In stand-alone CT imaging, contrast agents are applied to aid differentiation of anatomic structures, improve lesion localization, and support lesion characterizat...

CT) is a noninvasive radionuclide-based whole body imaging technique which combines both a Positron Emission Tomography (PET) scanner and an x-ray Computed Tomography (CT) scanner in a single gantry system. In PET, functional images are obtained which denotes spatial distribution of metabolic or biochemical activity in the body. These images are aligned with anatomical images obtained by CT sca...

Fluorodeoxyglucose-positron emission tomography (FDG-PET) and computed tomography (CT) have become the gold standard for staging of esophageal cancer by detecting distant metastases, but metastatic lymph nodes are often difficult to diagnose from the size and standardized uptake value (SUV). If we compare the diagnostic performance of endoscopic ultrasonography (EUS), CT, and FDG-PET in staging...

Magnetic resonance imaging (MRI)-negative epilepsy is associated with poor clinical outcomes prognosis. The present study was aimed to assess whether intracranial 3D interictal and ictal electroencephalography (EEG) findings, a combination of EEG at a different depth, in addition to clinical, scalp EEG, and positron emission tomography-computed tomography (PETCT) data help to predict outcome in...

Vertebral fractures (VF) and sacral insufficiency fractures (SIFs) are very common in osteoporotic patients with low-back pain and are often overlooked in clinical practice. Plain radiography is usually the first examination. However, on many occasions, further evaluation with CT scan, MRI and nuclear medicine studies is necessary. Nuclear medicine examinations have important applications for t...

To the Editor: Solitary splenic non-Hodgkin’s lymphoma (SSNHL) is a rare primary neoplasm; with an incidence less than 1% [1-3]. Authors have stated that solitary splenic lymphoma shows diffuse red pulp infiltration and enlargement without mass formation [1]. It cannot be pointed out by plain computed tomography (CT) or magnetic resonance imaging (MRI), ultrasounography (US) or Gallium-67 citra...