As a highly aggressive malignant disease, the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is poor. Yet, the mechanisms underlying the progression of PDAC remain unclear. MicroRNAs (miRNAs) may be involved in various human cancers as cancer suppressors or oncogenes. MicroRNA-183 (miR-183) was recently reported to be dysregulated in various types of cancer and to play an im...

OBJECTIVE To investigate outcome as measured by health status, disease process, and damage in an unselected group of patients with early rheumatoid arthritis (RA) monitored prospectively for 10 years and to search for prognostic factors. PATIENTS AND METHODS 183 patients with RA with disease duration <2 years were assessed annually at a team care unit. Health status was measured by the Health...

miR-183, a member of an evolutionarily conserved miRNA cluster (miR-96, miR-182, and miR-183), has been demonstrated to act as both a tumor suppressor and oncogene in various type of human cancer. However, the biological role of miR-183 in gastric cancer (GC) still remains unclear. In the present study, miR-183 expression was significantly decreased in gastric cancer tissues compared with its' ...

著者 らは,本 誌で,顎 運動を詳細に記録,再 現 する方法 として,Video方 式によるMultipoint XY-trackerの 応用1)について紹介し,次 いで頭部 動揺補正装置2)(digital autocanceller)を 考案 し て,各 個体の顎運動パターンを経年的に追跡 し, その変化の動態について観察 して きた。 その結 果,各 個体の運動のパターンは多種多様であ り, 特に成長発育中の被験者では,顎 運動を構成する 形態的因子の変化によっても,あ るいはまた,咬 合に参加 している乳歯の脱落や,後 継永久歯の咬 合への新たな参加,な どによっても変化 し,矯 正 治療によっても可変的であることが明らかになっ た。 しか し,こ こで対象とした顎運動 とは,切 歯 路(厳 密には下顎中切歯に装着 したtargetの 運 動路)の 記録であ り,し たがって...

In order to help readers stay up-to-date in the field, each issue of Progress Photovoltaics will contain a list recently published journal articles that are most relevant its aims and scope. This is drawn from an extremely wide range journals, including IEEE Journal Photovoltaics, Solar Energy Materials Cells, Renewable Energy, Sustainable Reviews, Applied Physics, Physics Letters. To assist re...

The study evaluated the commonly-used drugs for the management of sepsis and their outcome among under-five children. We evaluated the hospital-records of all paediatric sepsis patients (n = 183) in the intensive care unit (ICU) and longer-stay unit (LSU) of the Dhaka Hospital of icddr,b. These records were collected from the hospital management system (SHEBA) during November 2009 to October 20...

The Advanced Expert System (AES) was used in conjunction with the VITEK 2 automated antimicrobial susceptibility test system to ascertain the beta-lactam phenotypes of 196 isolates of the family Enterobacteriaceae and the species Pseudomonas aeruginosa. These isolates represented a panel of strains that had been collected from laboratories worldwide and whose beta-lactam phenotypes had been cha...

Identification of new sources of salt tolerance is particularly important to develop crop varieties suitable for saline soils. We evaluated 129 Pakistani and 58 exotic wheat landraces/cultivars grown in Hoagland's hydroponic nutrient solution, under control (tap water equivalent to 10 mM salt) and salt stress (200 mM NaCl) conditions. Forty-four genotypes were also tested under 250 mM NaCl...