نتایج جستجو برای: 17 alpha hydroxyprogesterone caproate

تعداد نتایج: 467684  

2013
Alex C Vidaeff Michael A Belfort

Prevention of preterm delivery is a major desiderate in contemporary obstetrics and a societal necessity. The means to achieve this goal remain elusive. Progesterone has been used in an attempt to prevent preterm delivery since the 1970s, but the evidence initially accumulated was fraught by mixed results and was based on mostly underpowered studies with variable eligibility criteria, including...

2014
Robert Egerman Risa Ramsey Niki Istwan Debbie Rhea Gary Stanziano

OBJECTIVE Gestational diabetes (GDM) and obesity portend a high risk for subsequent type 2 diabetes. We examined maternal factors influencing the development of gestational diabetes (GDM) in obese women receiving 17-alpha-hydroxyprogesterone caproate (17OHPC) for preterm delivery prevention. MATERIALS AND METHODS Retrospectively identified were 899 singleton pregnancies with maternal prepregn...

Journal: :Obstetrics and gynecology 2013
William A Grobman Sharon A Gilbert Jay D Iams Catherine Y Spong George Saade Brian M Mercer Alan T N Tita Dwight J Rouse Yoram Sorokin Kenneth J Leveno Jorge E Tolosa John M Thorp Steve N Caritis J Peter Van Dorsten

OBJECTIVE To estimate determinants of and outcomes associated with activity restriction among women with a short cervix. METHODS This was a secondary analysis of a randomized trial of 17-α hydroxyprogesterone caproate for prevention of preterm birth among nulliparous women with singleton gestations and cervices less than 30 mm by midtrimester ultrasonography. Women were asked weekly whether t...

2012
John L. Chollet Michael J. Jozwiakowski

The purpose of this study was to investigate the quality of hydroxyprogesterone caproate (HPC) active pharmaceutical ingredient (API) sources that may be used by compounding pharmacies, compared to the FDA-approved source of the API; and to investigate the quality of HPC injection samples obtained from compounding pharmacies in the US, compared to the FDA-approved product (Makena(®)). Samples o...

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