نتایج جستجو برای: 17 α

تعداد نتایج: 433827  

Journal: :Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 1990

2013
Alexander Munzer Ulrich Sack Roland Mergl Jeremias Schönherr Charlotte Petersein Stefanie Bartsch Kenneth C. Kirkby Katrin Bauer Hubertus Himmerich

The interplay between immune and nervous systems plays a pivotal role in the pathophysiology of depression. In depressive episodes, patients show increased production of pro-inflammatory cytokines such as interleukin (IL)-1β and tumor necrosis factor (TNF)-α. There is limited information on the effect of antidepressant drugs on cytokines, most studies report on a limited sample of cytokines and...

2017
Safa Alnahas Stefanie Hagner Hartmann Raifer Ayse Kilic Georg Gasteiger Reinier Mutters Anne Hellhund Immo Prinz Olaf Pinkenburg Alexander Visekruna Holger Garn Ulrich Steinhoff

Alterations of the airway microbiome are often associated with pulmonary diseases. For example, detection of the bacterial pathogen Moraxella catarrhalis in the upper airways is linked with an increased risk to develop or exacerbate asthma. However, the mechanisms by which M. catarrhalis augments allergic airway inflammation (AAI) remain unclear. We here characterized the cellular and soluble m...

Journal: :Current Biology 2012
Irini Topalidou Charles Keller Nereo Kalebic Ken C.Q. Nguyen Hannah Somhegyi Kristin A. Politi Paul Heppenstall David H. Hall Martin Chalfie

BACKGROUND Microtubules (MTs) are formed from the lateral association of 11-16 protofilament chains of tubulin dimers, with most cells containing 13-protofilament (13-p) MTs. How these different MTs are formed is unknown, although the number of protofilaments may depend on the nature of the α- and β-tubulins. RESULTS Here we show that the enzymatic activity of the Caenorhabiditis elegans α-tu...

2012
Gajendra Kumar Katara Nasim Akhtar Ansari Avninder Singh V. Ramesh Poonam Salotra

BACKGROUND Post kala-azar dermal leishmaniasis (PKDL), a dermal sequel of visceral leishmaniasis, caused by Leishmania donovani, constitutes an important reservoir for the parasite. Parallel functioning of counter acting immune responses (Th1/Th2) reflects a complex immunological scenario, suggesting the involvement of additional regulatory molecules in the disease pathogenesis. METHODOLOGY/P...

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