Growing evidence indicates that the endocannabinoid system is important for the acquisition and/or extinction of learning and memory. However, it is unclear which endocannabinoid(s) play(s) a crucial role in these cognitive functions, especially memory extinction. To elucidate the physiological role of 2-arachidonoylglycerol (2-AG), a major endocannabinoid, in behavioral and cognitive functions...

Carbenicillin and cefotaxime, two antibiotics commonly used for excluding Agrobacterium tumefaciens during plant transformation, were tested for their bacteriostatic effects as well as for their effects on plant regeneration in adventitious root explants of papaya following co-culture with Agrobacterium. A washing step with sterilized distilled water two days after co-culture enhanced the bacte...

The present study was conducted to examine the contamination of rivulet situated at Kasimpur, Aligarh (27.218° N; 79.378° E). It receives the wastewater of Harduaganj Thermal Power Plant (HTPS) containing fly ash and heavy metals. Among the heavy metals estimated in the rivulet water, Fe (8.71 mgL(-1)) was present in the highest concentration followed by Cu (0.86 mgL(-1)), Zn (0.30 mgL(-1)) Mn ...

Three genes, mgl A, B, and C, are required for active transport of substrate by the methylgalactose permease of E. coli K12. We report here that only two of these genes are required for substrate translocation, as seen by the ability or inability of isogenic mgl mutants (referred to as Tra+ and Tra minus, respectively) to grow on methyl-beta-D-galactopyranoside, supplied as sole carbon source. ...

Anaerobic treatment system was used for determination of colour removal under batch conditions. Azo-dye (Reactive Black 5, RB 5) with glucose as a carbon source was used as a synthetic wastewater. The decolourization process follows first order kinetics with respect to RB 5 azo-dye concentration in batch conditions. Decolourization rate constant (k1) value for dye concentration of 150 mgL was 0...

Magnesium isoglycyrrhizinate (MGL) is a new stereoisomer of glycyrrhizic acid, which is clinically used as a hepatoprotective medicine with more potent effects and less side effects than glycyrrhizic acid. This study was designed to evaluate the protective effects and possible mechanism of MGL against concanavalin A (Con A)-induced autoimmune hepatitis. Hepatitis was induced by Con A in C57/6J ...

Endocannabinoids function as retrograde messengers and modulate synaptic transmission through presynaptic cannabinoid CB1 receptors. The magnitude and time course of endocannabinoid signaling are thought to depend on the balance between the production and degradation of endocannabinoids. The major endocannabinoid 2-arachidonoylglycerol (2-AG) is hydrolyzed by monoacylglycerol lipase (MGL), whic...

We examine various versions of oriented cohomology and BorelMoore homology theories in algebraic geometry and put these two together in the setting of an “oriented duality theory”, a generalization of Bloch-Ogus twisted duality theory. We apply this to give a Borel-Moore homology version MGL ∗,∗ of Voevodsky’s MGL-theory, and a natural map θ : Ω∗ → MGL 2∗,∗ , where Ω∗ is the algebraic cobordism...

The endogenous cannabinoids (endocannabinoids) are lipid molecules that may mediate retrograde signaling at central synapses and other forms of short-range neuronal communication. The monoglyceride 2-arachidonoylglycerol (2-AG) meets several criteria of an endocannabinoid substance: (i) it activates cannabinoid receptors; (ii) it is produced by neurons in an activity-dependent manner; and (iii)...