AIM Prostate cancer is the most commonly diagnosed malignancy and the second most common cause of cancer deaths in the Western male population. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) modulate the remodeling of the extracellular matrix (ECM). The imbalance between MMPs and TIMPs may lead to an emergence of pathological processes such as cancer. In this study, the ...

Objective: Idiopathic scoliosis is the most common pediatric spinal deformity affecting 1% to 3% of the population, and adolescent idiopathic scoliosis (AIS) accounts for approximately 80% of these cases, however, the etiology and pathogenesis of AIS are still uncertain. The current study aims to identify the relationship between MMP2 and AIS predisposition, to investigate the major effect of M...

BACKGROUND Although superficial varices of lower extremities with high morbidity are common, their etiology has not been elucidated yet. Previously, it was thought that venous hypertension was responsible for such cases by causing valvular insufficiency, but recent findings indicate that the changes in the venous wall structure might be main initiating factors. Matrix metalloproteinase enzyme-2...

Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity against matrix proteins, particularly basement membrane constituents. A single nucleotide polymorphism (SNP) at -1306, which disrupts a Sp1-type promoter site (CCACC box), displayed a strikingly lower promoter activity with the T allele. In the present study, we investigate whether this MMP-2 SNP is associated with suscep...

En lo sustancial vemos que la Constitución Política de 1991 trajo consigo una serie cambios en las estructuras socio-culturales dieron origen a muchas normas, entre cuales destacamos para este trabajo particular Ley 1306 del 2009, surge como respuesta necesidad mejorar condiciones jurídicas los incapaces por discapacidad mental y adaptarlas. jurídico, encontramos declaratoria interdicción se de...

A twenty-eight day floor pen experiment was carried out using 1680 Cobb-500 male day old chicks to evaluate the impact of feeding different particle sizes of calcium carbonate (CaCO ) on broiler performance 3 and tibia ash. The experiment consisted of 8 treatments with 6 replications per treatment to test 8 different CaCO particle sizes. The corn-soybean meal based diets contained 21.5% CP, 302...

Z. Naturforsch. 41 a, 1302-1306 (1986); received August 7, 1986 The microwave ground state spectra of tert.-butyl isocyanide, (CH3)3CNC, and phenyl isocyanide, C6H 5NC, have been measured by microwave Fourier transform spectroscopy in the region 5.0 to 8.0 GHz and analysed for nuclear quadrupole hyperfine splitting due to ‘*N. The nuclear quadrupole coupling constants are shown to be in accorda...