Links [1] http://www.sba.unipi.it/it/sba/organizzazione/segreteria-amministrativa [2] http://www.sba.unipi.it/it/sba/personale/tacchi-franca [3] mailto:franca&# 46;tacchi@sba.un&#105 ;pi.it [4] http://www.sba.unipi.it/it/sba/personale/bertela-pier-carla [...

Editorial G&R

Links [1] http://www.sba.unipi.it/it/sba/organizzazione/segreteria-amministrativa [2] http://www.sba.unipi.it/it/sba/personale/tacchi-franca [3] mailto:franca&# 46;tacchi@sba.un&#105 ;pi.it [4] http://www.sba.unipi.it/it/sba/personale/bertela-pier-carla [...

2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA) induced growth inhibition in human cancer cells using the national cancer institute (NCI) anticancer drug screen. In our previous study, we demonstrated that DPA exerted growth inhibitory activities in the three human colon cancer cell lines (Colo 205, HT-29, and HCT-15). To identify the detailed mechanism, we examined the function...

Previously, we reported an association of mitomycin C resistance and a deficiency of NAD(P)H:quinone oxidoreductase (NQO1) in HCT 116-R30A cells, a subline derived from mitomycin C-sensitive HCT 116 cells. In HCT 116 cells, we found two mRNAs coding full-length cDNAs of NQO1 differing at codon 139, one with arginine (wild type), and one with tryptophan. Only the tryptophan 139 form of mRNA was ...