Given a family F of r-graphs, let ex(n,F) be the maximum number of edges in an n vertex r-graph containing no member of F . Let C 4 denote the family of r-graphs with distinct edges A,B, C, D, such that A ∩ B = C ∩ D = ∅, A ∪ B = C ∪ D. For s1 ≤ · · · ≤ sr, let K(s1, . . . , sr) be the complete r-partite r-graph with parts of sizes s1, . . . , sr. Füredi conjectured over 15 years ago that ex(n,...

CONTENTS 1.0 Introduction 1.1 Definitions 1.1.1 Validation 1.1.2 Method of analysis 1.1.3 Performance characteristics of a method of analysis 2.0 Single-Laboratory Validation Work 2.1 Preparation of the Laboratory Sample 2.2 Identification 2.3 Method of Analysis or Protocol 2.3.1 Optimization 2.3.2 Reference standard 2.3.3 Ruggedness Trial 2.3.4 Specific variables a. Analyte addition b. Reextra...

Density functional theory is used to find incremental fragmentation energy, overall dissociation energy, and average monomer fragmentation energy of cyclic gold(I) thiolate clusters and anionic chain structures of gold(I) and silver(I) thiolate clusters as a measure of the relative stability of these systems. Two different functionals, BP86 and PBE, and two different basis sets, TZP and QZ4P, a...

Continental crust is too Si-rich and Mg-poor to derive directly from mantle melting, which generates basaltic rather than felsic magmas. Converting basalt to more felsic compositions requires a second step involving Mg loss, which is thought to be dominated by internal igneous differentiation. However, igneous differentiation alone may not be able to generate granites, the most silicic endmembe...

Protein movements underlying ligand-gated ion channel activation are poorly understood. The binding of agonist initiates a series of conformational movements that ultimately lead to the opening of the ion channel pore. Although little is known about local movements within the GABA-binding site, a recent structural model of the GABA(A) receptor (GABA(A)R) ligand-binding domain predicts that beta...

Designing a protein sequence that will fold into a predefined structure is of both practical and fundamental interest. Many successful, computational designs in the last decade resulted from improved understanding of hydrophobic and polar interactions between side chains of amino acid residues in stabilizing protein tertiary structures. However, the coupling between main-chain backbone structur...

La1-xSrxAlO3 (x=0 to 0.4) perovskite materials were synthesized by the reverse strike co-precipitation method and their soot oxidation activity was evaluated. All the catalysts synthesized were characterized using XRD, BET specific surface area, FESEM and XPS techniques. As analyzed by XRD, La1-xSrxAlO3 <...

In this study, formic acid (FA) was employed as an in-situ hydrogen donor for the reductive de-polymerization of kraft lignin (KL). Under the optimum operating conditions, i.e., 300 °C, 1 h, 18.6 wt.% substrate concentration, 50/50 (v/v) water-ethanol medium with FA at a FA-to-lignin mass ratio of 0.7, KL (Mw∼10,000 g/mol) was effectively de-polymerized, producing de-polymerized lignin (DL, Mw ...