this paper uses integrated data envelopment analysis (dea) models to rank all extreme and non-extreme efficient decision making units (dmus) and then applies integrated dea ranking method as a criterion to modify genetic algorithm (ga) for finding pareto optimal solutions of a multi objective programming (mop) problem. the researchers have used ranking method as a shortcut way to modify ga to d...

Microblogging services have become popular, especially since smartphones made them easily accessible for common users. However, current services like Twitter rely on a centralized infrastructure, which has serious drawbacks from privacy and reliability perspectives. In this paper, we present a decentralized privacy-preserving microblogging infrastructure based on a distributed peer-to-peer netw...

A number of studies have demonstrated that cytochrome P450 (P450) converts furanocoumarin derivatives into reactive molecules, which form covalent bonds to biomolecules. 5-Methoxypsoralen (5-MOP) is a natural furanocoumarin from apiaceous plants. In this study, we examined the effect on 5-MOP metabolism of single nucleotide polymorphisms (SNPs) in CYP2A13. We used Escherichia coli-generated rec...

Activation of brain nociceptin/orphanin FQ (NOP) receptors leads to attenuation of mu-opioid receptor (MOP receptor)-mediated antinociception. Buprenorphine, a high-affinity partial MOP receptor agonist also binds to NOP receptors with 80 nM affinity. The buprenorphine-induced inverted U-shaped dose-response curve for antinociception may be due to NOP receptor activation, given that, in the pre...

The effects of the phototoxic K+- channel blockers 8-methoxypsoralen (8-MOP) and 5-methoxypsoralen (5-MOP) on Ranvier nodes were compared to those of 5,8-diethoxypsoralen (5,8-EOP) by means of the Hodgkin-Huxley formalism. When these test substances were added individually to the bathing solution (8-MOP: 100 micromol/l; 5-MOP: 50 micromol/l; 5,8-EOP: 10 micromol/l) the following completely reve...

Nociceptin/orphanin FQ peptide receptor (NOP) agonists produce antinociceptive effects in animal models after spinal administration and potentiate μ-opioid receptor (MOP)-mediated antinociception. This study determined the antinociceptive effects of spinally administered bifunctional NOP/MOP ligands and the antinociceptive functions of spinal NOP and MOP receptors in mice. Antinociceptive effec...

This paper uses integrated Data Envelopment Analysis (DEA) models to rank all extreme and non-extreme efficient Decision Making Units (DMUs) and then applies integrated DEA ranking method as a criterion to modify Genetic Algorithm (GA) for finding Pareto optimal solutions of a Multi Objective Programming (MOP) problem. The researchers have used ranking method as a shortcut way to modify GA to d...

The effect of potash biofertilizer and chemical fertilizer was studied on quantitative and qualitative traits of periwinkle in a factorial experiment based on a Randomized Complete Design with three replications, 48 experimental units, and two factors: (1) different methods of potash bio-fertilizer application at four levels of control (B0), seed inoculation (B1), root inoculation (B2) and seed...

This note is motivated by the similarity between multiobjective programming (MOP) and bargaining theory. It uses the known MOP concepts to establish two new bargaining results: (1) the efficiency of KalaiSmorodinsky (KS) and Nash (NA) solutions for large classes of bargaining problems can be refined to the sharper concept of proper efficiency; (2) the independence of irrelevant alternatives (II...