Implantation metastasis from a colorectal cancer into a perianal fistula is very rare. Such lesions are commonly mistaken as benign perianal abscesses or fistulas and diagnosed only after pathological analysis of surgically excised fistulas. Once diagnosed, the management of this condition remains controversial. We report a case of perianal fistula that was unexpectedly found to harbor adenocar...

BACKGROUND Crohn's disease (CD) is a chronic idiopathic inflammatory bowel disease involving the whole gastrointestinal tract. TNFSF15 has been proved as a susceptibility gene for CD, but there are few reports about the association between TNFSF15 single nucleotide polymorphisms (SNPs) and the clinical course of CD. AIM To investigate the association between TNFSF15 genotypes and the clinical...

The patient underwent EUA rectum; no abscess, fissure or fistula was found. Rigid sigmoidoscopy revealed diffuse non-specific redness of the rectal mucosa just beyond the dentate line. Random biopsies were taken. Post operatively the patient continued to experience severe pain and remained incontinent. Pathology showed multiple fragments of rectal mucosa heavily infiltrated by a diffuse and she...

Perianal mucinous adenocarcinoma is a rare tumor which may be associated with long-standing chronic perianal sepsis. Early diagnosis is challenging and is based on a high index of clinical suspicion and specific histological features. Definitive treatment is surgical, in the form of an abdomino-perineal resection. We hereby describe a case of a perianal mucinous adenocarcinoma arising from long...

Treatment of perianal fistulas in Crohn's disease should be defined on an individual basis. A combined medical and surgical approach is the optimal treatment. Adequate management of perianal fistula disease is based on the presence or absence of active proctitis, anatomic location, and fistula type. Furthermore, the presence of perianal abscesses must be ruled out. This evaluation includes digi...

Abstract Background Perianal fistulas are common and cause significant quality of life impairment in patients (pts) with Crohn’s disease (CD). In previous phase 2/3 studies, ustekinumab (UST) showed some evidence efficacy on fistula resolution, no clear dose-response relationship. Additional studies needed to evaluate the role UST perianal treatment. Here, we report data from two recent CD, SEA...

BACKGROUND Although many attempts have been made to advance the treatment of complex anal fistula, it continues to be a difficult surgical problem. This study aimed to describe the novel technique of video-assisted anal fistula treatment (VAAFT) and our preliminary experiences using VAAFT with patients with complex anal fistula. MATERIAL AND METHODS From May 2015 to May 2016, 52 patients with c...

AIM OF THE STUDY The aim of this study was assessment of the contemporary outcomes of oesophageal atresia (OA) in a national paediatric surgical centre. PATIENTS AND METHODS A review of the hospital records of all patients who underwent repair of oesophageal atresia (OA) in our institute between 1991 and 2011 was performed. RESULTS The study included 130 consecutive infants with OA: types A...

Abstract Purpose To report our experience with endoscopic Thulium LASER for treatment of recurrent TEF after EA surgery, and H-Type fistulas. Methods A retrospective chart review consecutive patients undergoing standardized closure as first line therapy tracheoesophageal fistula (RTEF) H-type using LASER, from 2013 to 2019, in a pediatric tertiary care center. Control procedure was systematical...

Abstract Background Perianal sepsis and fistulas are common lesions. Fistula-in-ano is a tedious problem because of high recurrence rates severe unexpected complications postoperatively. Many imaging modalities used to evaluate this area. Magnetic resonance (MRI) has been considered the gold standard procedure for perianal fistula assessment, i.e., it provides surgeon with an accurate roadmap s...