The ability of ethanol to affect the regional distribution of individual glutathione S-transferase (GST) isoenzymes in rat liver was investigated by analyzing the expression levels in cell lysates obtained from the periportal or perivenous liver region after in situ digitonin perfusion. In control rats, a significant perivenous dominance of GST proteins and activities measured by the substrates...

Reduction of nitrobenzene, 4-ethyl nitrobenzene, 4-isopropyl nitrobenzene, 4-nitro 1-phenyl acetate, acetophenone, with CuCl2/MeOH/NaBH4 provided hydrogenated products in quantitative yields. In order to evaluate the best catalytic systems various transition metal catalysts were examined for the first time and CuCl2 catalysts was superactive system. And a solvent system was also studied with me...

Evidence is presented that ligandin, an intracellular protein involved in the binding of such anions as bilirubin, indocyanine green, and penicillin, is identical to glutathione S-transferase B (EC 2.5.1.18), an enzyme catalyzing the conjugation of glutathione with such electrophiles as 1-chloro-2,4-dinitrobenzene, 1,2-dichloro-4-nitrobenzene, iodomethane, ethacrynic acid, and bromosulfophthale...