Alkanols are small aliphatic compounds that inhibit voltage-gated K(+) (K(v)) channels through a yet unresolved gating mechanism. K(v) channels detect changes in the membrane potential with their voltage-sensing domains (VSDs) that reorient and generate a transient gating current. Both 1-Butanol (1-BuOH) and 1-Hexanol (1-HeOH) inhibited the ionic currents of the Shaker K(v) channel in a concent...

[1] Both surface and volume uptake can contribute to the removal of tropospheric gases by ice-phase precipitation and cloud particles. These processes were evaluated by depositing ice in the presence of several gaseous oxyhydrocarbons and analyzing the chemical composition of the deposit. Acetone, methanol, ethanol, n-propanol, n-butanol, tert-butanol, cyclohexanol, and toluene were tested. Vol...

We address here the manner in which acid catalysis senses the strength of solid acids. Acid strengths for Keggin polyoxometalate (POM) clusters and zeolites, chosen because of their accurately known structures, are described rigorously by their deprotonation energies (DPE). Mechanistic interpretations of the measured dynamics of alkane isomerization and alkanol dehydration are used to obtain ra...

The hydrocarbonoclastic bacterium Acinetobacter venetianus RAG-1 has attracted substantial attention due to its powerful oil-degrading capabilities and its potential to play an important ecological role in the cleanup of alkanes. In this study, we compare the transcriptome of the strain RAG-1 grown in dodecane, the corresponding alkanol (dodecanol), and sodium acetate for the characterization o...

Enzymes of the AlkB and CYP153 families catalyze the first step in the catabolism of medium-chain-length alkanes, selective oxidation of the alkane to the 1-alkanol, and enable their host organisms to utilize alkanes as carbon sources. Small, gaseous alkanes, however, are converted to alkanols by evolutionarily unrelated methane monooxygenases. Propane and butane can be oxidized by CYP enzymes ...

Abutilon indicum (Linn) family Malvaceae, commonly known as Atibala is an important medicinal plant. The whole plant as well as specific part such as root, leaves, and flower is used to treat various health ailments. It is found as a weed in sub-Himalayan tracts, hills up to 1200 m and in hotter parts of India. The plant is found to possess immunodulatory, anticonvulsant, larvicidal, Lipid lowe...